Evidence map›Paper›PMID 37393269›Full record

Trial reportBMC musculoskeletal disorders2023

Cardiac output and arteriovenous oxygen difference contribute to lower peak oxygen uptake in patients with fibromyalgia.

Taneli Lehto, Teemu Zetterman, Ritva Markkula, Jari Arokoski, Heikki Tikkanen, Eija Kalso, Juha E Peltonen

Registry-linked trialOpen access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03300635 (Metaboliset Muutokset ja Lihastoiminta Fibromyalgiassa), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03300635 nacompletednot on this map

Metaboliset Muutokset ja Lihastoiminta Fibromyalgiassa

TypeinterventionalSponsorHelsinki University Central HospitalRan2015 to 2019Enrolled81ConditionsFibromyalgiaArmsMental distress and relaxation test, Glucose tolerance test, Exercise test
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Taneli Lehto *Department of Sports and Exercise Medicine, Clinicum, University of Helsinki, Mäkelänkatu 47, Urhea-Hall, 00550, Helsinki, Finland. taneli.lehto@helsinki.fi.ORCID http://orcid.org/0000-0002-4428-1401
Teemu Zetterman *Department of Anaesthesiology, Intensive Care and Pain Medicine, Pain Clinic, Helsinki University and Helsinki University Hospital, Helsinki, Finland.
Ritva MarkkulaDepartment of Anaesthesiology, Intensive Care and Pain Medicine, Pain Clinic, Helsinki University and Helsinki University Hospital, Helsinki, Finland.
Jari ArokoskiDepartment of Physical and Rehabilitation Medicine, Helsinki University Hospital and Helsinki University, Helsinki, Finland.
Heikki TikkanenSports and Exercise Medicine, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Eija Kalso *Department of Anaesthesiology, Intensive Care and Pain Medicine, Pain Clinic, Helsinki University and Helsinki University Hospital, Helsinki, Finland.
Juha E Peltonen *Department of Sports and Exercise Medicine, Clinicum, University of Helsinki, Mäkelänkatu 47, Urhea-Hall, 00550, Helsinki, Finland.
University of Helsinki · FIHelsinki University Hospital · FIUniversity of Eastern Finland · FI

Funding

Finnish State Research Funding TYH2017215Helsingin ja Uudenmaan Sairaanhoitopiiri HUS 174/2019 § 1Helsingin ja Uudenmaan Sairaanhoitopiiri HUS 76/2018 § 11
6 · The paper itself

Abstract

backgroundPatients with fibromyalgia (FM) exhibit low peak oxygen uptake ([Formula: see text]O

methodsThirty-five women with FM, aged 23 to 65 years, and 23 healthy controls performed a step incremental cycle ergometer test until volitional fatigue. Alveolar gas exchange and pulmonary ventilation were measured breath-by-breath and adjusted for fat-free body mass (FFM) where appropriate. [Formula: see text] (impedance cardiography) was monitored. [Formula: see text] was calculated using Fick's equation. Linear regression slopes for oxygen cost (∆[Formula: see text]O

results[Formula: see text]O

conclusionsBoth [Formula: see text] and C(a-v)O

trial registrationClinicalTrials.gov, NCT03300635. Registered 3 October 2017-Retrospectively registered. https://clinicaltrials.gov/ct2/show/NCT03300635 .

Indexed as

FibromyalgiaCardiac OutputCase-Control StudiesExerciseFatigueFemaleHumansOxygenOxygenCardiopulmonary exercise testImpedance cardiographyLeisure-time physical activityOxygen costVentilatory threshold

Identifiers

PMID37393269
PMCPMC10314615
OpenAlexW4382797231

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.