Evidence map›Paper›PMID 37392735›Full record

ArticleImmunity2023

CXCR3 expression in regulatory T cells drives interactions with type I dendritic cells in tumors to restrict CD8

Mariela A Moreno Ayala, Timothy F Campbell, Chenyu Zhang, Noa Dahan, Alissa Bockman, Varsha Prakash, Lawrence Feng, Theo Sher, Michel DuPage

Open access · bronzeAbstract read
In one paragraph

Article in Immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 164 papers.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed
36.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 196 citations in OpenAlex.

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  20. Regulatory T cells in cancer and inflammation.Signal transduction and targeted therapy · 2026
    Review

104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mariela A Moreno AyalaDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Timothy F CampbellDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Chenyu ZhangDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Noa DahanDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Alissa BockmanDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Varsha PrakashDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Lawrence FengDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Theo SherDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Michel DuPageDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: dupage@berkeley.edu.
University of California, Berkeley · USMolecular Sciences Institute · US

Funding

Immunology & Pathogenesis Program Training GrantT32AI100829 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Gregory M Barton, ELLEN A ROBEY · 2012 to 2026
$4.7M
Engineering precision cancer immunotherapyDP2CA247830 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI DUPAGE, MICHEL · 2019 to 2019
$2.4M
NCI NIH HHS DP2 CA247830NIAID NIH HHS T32 AI100829
6 · The paper itself

Abstract

Infiltration of regulatory T (Treg) cells, an immunosuppressive population of CD4

Indexed as

NeoplasmsT-Lymphocytes, RegulatoryCD8-Positive T-LymphocytesDendritic CellsHumansImmunotherapyReceptors, CXCR3CXCR3 protein, humanReceptors, CXCR3cancercheckpoint blockadecross presentationCXCR3dendritic cellsimmunotherapyregulatory T cellsTregs

Identifiers

PMID37392735
PMCPMC10752240
OpenAlexW4382680794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.