Evidence map›Paper›PMID 37392712›Full record

ArticleInternational journal of medical informatics2023

Leveraging natural language processing to identify eligible lung cancer screening patients with the electronic health record.

Siru Liu, Allison B McCoy, Melinda C Aldrich, Kim L Sandler, Thomas J Reese, Bryan Steitz, Jiang Bian, Yonghui Wu, Elise Russo, Adam Wright

Abstract read
In one paragraph

Article in International journal of medical informatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  6. Artificial intelligence in preventive care in primary health care settings: a scoping review.Archives of medical sciences. Atherosclerotic diseases · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Siru LiuDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: siru.liu@vumc.org.
Allison B McCoyDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Melinda C AldrichDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Kim L SandlerDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Thomas J ReeseDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Bryan SteitzDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Jiang BianDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.
Yonghui WuDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.
Elise RussoDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Adam WrightDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

Safety Promotion through Early Event Detection in the Elderly (SPEEDe)R01AG062499 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WRIGHT, ADAM T · 2019 to 2023
$3.5M
Optimizing Clinical Decision Support Alerts Using Explainable Artificial Intelligence (XAI)K99LM014097 · NLM · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LIU, SIRU · 2022 to 2022
$90k
NIA NIH HHS R01 AG062499NLM NIH HHS K99 LM014097
6 · The paper itself

Abstract

objectiveTo develop and validate an approach that identifies patients eligible for lung cancer screening (LCS) by combining structured and unstructured smoking data from the electronic health record (EHR).

methodsWe identified patients aged 50-80 years who had at least one encounter in a primary care clinic at Vanderbilt University Medical Center (VUMC) between 2019 and 2022. We fine-tuned an existing natural language processing (NLP) tool to extract quantitative smoking information using clinical notes collected from VUMC. Then, we developed an approach to identify patients who are eligible for LCS by combining smoking information from structured data and clinical narratives. We compared this method with two approaches to identify LCS eligibility only using smoking information from structured EHR. We used 50 patients with a documented history of tobacco use for comparison and validation.

results102,475 patients were included. The NLP-based approach achieved an F1-score of 0.909, and accuracy of 0.96. The baseline approach could identify 5,887 patients. Compared to the baseline approach, the number of identified patients using all structured data and the NLP-based algorithm was 7,194 (22.2 %) and 10,231 (73.8 %), respectively. The NLP-based approach identified 589 Black/African Americans, a significant increase of 119 %.

conclusionWe present a feasible NLP-based approach to identify LCS eligible patients. It provides a technical basis for the development of clinical decision support tools to potentially improve the utilization of LCS and diminish healthcare disparities.

Indexed as

Lung NeoplasmsEarly Detection of CancerElectronic Health RecordsHumansNatural Language ProcessingSmokingElectronic health recordLung cancer screeningNatural language processing

Identifiers

PMID37392712
PMCPMC11537206

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.