ArticleVeterinary medicine and science2023
Preliminary phytochemical screening and antibacterial effects of root bark of Ferula communis (Apiaceae).
Article in Veterinary medicine and science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Article
- Optimization and HPLC-DAD Characterization of Phenolic Compounds and Antioxidant Activity inMolecules (Basel, Switzerland) · 2026Article
- In-vitro antibacterial activity of methanolic extract ofVeterinary and animal science · 2026Article
- Structural analysis and antimicrobial assessment of bioinspired silver nanoparticles from Ferula communis.Scientific reports · 2025Article
- Exploring the Therapeutic Potential and Toxicological Risks of Four Ethnomedicinal Plants from Hakkâri (Southeastern Turkey): A First Comprehensive Analytical and Microstructural Evaluation.Plants (Basel, Switzerland) · 2025Article
- In vitro antibacterial activity of Bersama abyssinica Fresen crude extract against representative Gram-positive and Gram-negative bacterial isolates.Veterinary medicine and science · 2024Article
- Preliminary phytochemical screening and antibacterial effects of root bark of Ferula communis (Apiaceae).Veterinary medicine and science · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPlants are widely used in traditional medicine because they contain a high concentration of antimicrobial agents, serving as the foundation for medicines. The aim of this study was preliminary identification of phytochemicals and assesses the antimicrobial activity of extracts of Ferula communis root bark.
methodsPlant was collected, and standard qualitative procedures were conducted. The plant samples were extracted with 99.9% methanol and 80% ethanol. To identify phytochemicals found in plants, a preliminary phytochemical analysis was performed. Agar diffusion tests, minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) were performed to evaluate antibacterial activity.
resultThe preliminary phytochemical analysis of the ethanol and methanol extract revealed positive results for flavonoids, coumarins and tannins. Terpenoids and anthraquinones were detected only in the methanol extract. The extract of Ferula communis showed an antibacterial effect on both gram-negative and gram-positive bacteria in a concentration-dependent manner. The average zone of inhibition for gram-positive bacteria was 11 mm, whereas for gram-negative bacteria, it was 9 mm. The MIC and MBC values also varied with the type of bacteria. In all bacterial species tested, the mean MBC value was similar to the MIC.
conclusionDifferent phytochemicals were detected in extracts of the root bark of F. communis and extracts showed antibacterial effects in a concentration-dependent manner. Therefore, further purification and evaluation of the extracts and antioxidant activity of the plant should be investigated.
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