Evidence map›Paper›PMID 37392293›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2023

Antimicrobial activity of cinnamaldehyde against multidrug-resistant Klebsiella pneumoniae: an in vitro and in vivo study.

Marcia Soares Mattos Vaz, Gleyce Hellen de Almeida de Souza, Joyce Alencar Dos Santos Radai, Thiago Leite Fraga, Gustavo Gomes de Oliveira, Heberton Wender, Kesia Esther da Silva, Simone Simionatto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Antimicrobial efficacy of cinnamaldehyde combined with polymyxin B against carbapenem- polymyxin-resistant Klebsiella pneumoniae.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcia Soares Mattos VazLaboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Cidade Universitária, Itahum, Km 12, Dourados, Mato Grosso Do Sul, CEP: 79804970, Brazil.
Gleyce Hellen de Almeida de SouzaLaboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Cidade Universitária, Itahum, Km 12, Dourados, Mato Grosso Do Sul, CEP: 79804970, Brazil.
Joyce Alencar Dos Santos RadaiLaboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Cidade Universitária, Itahum, Km 12, Dourados, Mato Grosso Do Sul, CEP: 79804970, Brazil.
Thiago Leite FragaCentro Universitário da Grande Dourados-UNIGRAN, Dourados, Mato Grosso Do Sul, Brazil.
Gustavo Gomes de OliveiraCentro Universitário da Grande Dourados-UNIGRAN, Dourados, Mato Grosso Do Sul, Brazil.
Heberton WenderGrupo de Pesquisa Em Nano E Fótons, Instituto de Física, Universidade Federal de Mato Grosso Do Sul, Campo Grande, Brazil.
Kesia Esther da SilvaLaboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Cidade Universitária, Itahum, Km 12, Dourados, Mato Grosso Do Sul, CEP: 79804970, Brazil.
Simone SimionattoLaboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Cidade Universitária, Itahum, Km 12, Dourados, Mato Grosso Do Sul, CEP: 79804970, Brazil. simonesimionatto@ufgd.edu.br.ORCID http://orcid.org/0000-0003-2367-0915

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 313742/2018-9Conselho Nacional de Desenvolvimento Científico e Tecnológico 408778/2022-9Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul 71/031.898/2022
6 · The paper itself

Abstract

The emergence and spread of multidrug-resistant (MDR) Klebsiella pneumoniae strains have increased worldwide, posing a significant health threat by limiting the therapeutic options. This study aimed to investigate the antimicrobial potential of cinnamaldehyde against MDR-K. pneumoniae strains in vitro and in vivo assays. The presence of resistant genes in MDR- K. pneumoniae strains were evaluated by Polymerase Chain Reaction (PCR) and DNA sequencing. Carbapenem-resistant K. pneumoniae strains show the bla

Indexed as

Anti-Infective AgentsKlebsiella InfectionsAcroleinAnimalsAnti-Bacterial AgentsCarbapenemsDrug Resistance, Multiple, BacterialKlebsiella pneumoniaeMiceMicrobial Sensitivity TestsPolymyxinsAcroleinAnti-Bacterial AgentsAnti-Infective AgentsCarbapenemscinnamaldehydePolymyxinsCinnamaldehydeGram-negativeInfectionMultidrug-resistant

Identifiers

PMID37392293
PMCPMC10485196

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.