Evidence map›Paper›PMID 37392258›Full record

ArticleInternational ophthalmology2023

Optical coherence tomography angiography findings in pediatric patients with graves ophthalmopathy.

Kubra Serbest Ceylanoglu, Emine Malkoc Sen, Selin Sahin Karamert, Senay Savas Erdeve, Semra Cetinkaya

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In one paragraph

Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kubra Serbest CeylanogluUniversity of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey. kubraceylanoglu@gmail.com.ORCID http://orcid.org/0000-0001-8511-7504
Emine Malkoc SenUniversity of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0002-5373-8987
Selin Sahin KaramertUniversity of Health Sciences, Dr. Sami Ulus Obstetrics and Gynaecology, Children's Health and Disease Education and Research Hospital, Ophthalmology Department, Ankara, Turkey.ORCID http://orcid.org/0000-0002-0957-1139
Senay Savas ErdeveUniversity of Health Science, Dr. Sami Ulus Obstetrics and Gynaecology, Children's Health and Disease Education and Research Hospital, Clinic of Pediatric Endocrinology, Ankara, Turkey.ORCID http://orcid.org/0000-0002-4164-5089
Semra CetinkayaUniversity of Health Science, Dr. Sami Ulus Obstetrics and Gynaecology, Children's Health and Disease Education and Research Hospital, Clinic of Pediatric Endocrinology, Ankara, Turkey.ORCID http://orcid.org/0000-0003-3974-2872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate peripapillary, macular microvascular structure, and retinal nerve fiber layer (RNFL) thickness profile in children with Graves Ophthalmopathy (GO). MATERIAL AND

methodsThirty-six eyes of 18 children with GO were prospectively compared with 40 eyes of 20-age and sex-matched controls. The severity and activity of the disease were evaluated according to the criteria of the European Group on Graves' Ophthalmopathy (EUGOGO) and Clinical Activity Score (CAS). After complete ophthalmologic and endocrinologic examination, all patients underwent optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) measurements. Retinal nerve fiber layer (RNFL) thickness, macular superficial capillary plexus (SCP), deep capillary plexus (DCP), foveal avascular zone (FAZ) area, acircularity index (AI) of the FAZ and peripapillary microvascular structure were analyzed.

resultsThe mean age was 12.1 ± 2.4 years in the GO group and 11.2 ± 2.6 years in healthy control group (p = 0.11). Duration of disease was 8.9 ± 4.2 months in the GO group. All patients in GO group had mild and inactive ophthalmopathy. In temporal inferior quadrant, RNFL thickness was significantly thinner in the GO group compared to the control group (p = 0.03). No significant difference was seen between groups both peripapillary and macular microvascular structure (all p > 0.05).

conclusionGO has no effect on optic nerve thickness, peripapillary and macular vascular parameters except inferior temporal RNFL in children.

Indexed as

Graves OphthalmopathyTomography, Optical CoherenceAdolescentAngiographyChildFluorescein AngiographyHumansRetinaRetinal VesselsOptical coherence tomography angiographyPediatric graves ophthalmopathyRetinal nerve fiber layer

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.