Evidence map›Paper›PMID 37391810›Full record

ArticleEye and vision (London, England)2023

Incidence and characteristics of aqueous misdirection after glaucoma surgery in Chinese patients with primary angle-closure glaucoma.

Haishuang Lin, Jiaqian Li, Xuanli Zheng, Rui Wan, Mengtian Zhou, Yutong Ding, Yiting Ji, Yanqian Xie, Clement C Tham, Shaodan Zhang and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Eye and vision (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. The pseudo plateau iris: A review.Indian journal of ophthalmology · 2026
    Review
  3. Article
  4. In vivo assessment of Berger's space in primary angle closure disease using AS-OCT: a comparative study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Observational
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Haishuang LinWenzhou Medical University, Wenzhou, 325027, China.
Jiaqian LiWenzhou Medical University, Wenzhou, 325027, China.
Xuanli ZhengWenzhou Medical University, Wenzhou, 325027, China.
Rui WanWenzhou Medical University, Wenzhou, 325027, China.
Mengtian ZhouWenzhou Medical University, Wenzhou, 325027, China.
Yutong DingWenzhou Medical University, Wenzhou, 325027, China.
Yiting JiWenzhou Medical University, Wenzhou, 325027, China.
Yanqian XieNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, No. 270, Xue Yuan Xi Road, Wenzhou, 325027, Zhejiang, China.
Clement C ThamDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Shaodan ZhangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, No. 270, Xue Yuan Xi Road, Wenzhou, 325027, Zhejiang, China. shaodan_zhang_wmu@126.com.
Yuanbo LiangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, No. 270, Xue Yuan Xi Road, Wenzhou, 325027, Zhejiang, China. yuanboliang@126.com.ORCID http://orcid.org/0000-0001-9685-7356
Wenzhou Medical University · CNChinese University of Hong Kong · HK

Funding

key innovation and guidance program of the Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University YNZD2201903Key Research and Development Projects of Zhejiang Province 2022C03112the Basic Scientific Research Program of Wenzhou Y2020365the National Key Research and Development Project of China 2020YFC2008200the Program for Zhejiang Leading Talent of S&T Innovation 2021R52012
6 · The paper itself

Abstract

backgroundTo report the incidence and clinical characteristics of aqueous misdirection (AM) after glaucoma surgery in Chinese patients with primary angle-closure glaucoma.

methodsMedical records of all patients diagnosed with primary angle-closure glaucoma who underwent glaucoma surgery in the Eye Hospital of Wenzhou Medical University between January 2012 and December 2021 were retrospectively reviewed. Cases of AM were identified through a keyword-based search. The incidence of AM was calculated. Demographic and clinical characteristics of the AM patients were also described.

resultsA total of 5044 eyes with primary angle-closure glaucoma were included (mean age 65.81 ± 9.96 years, 68.11% women). Thirty-eight eyes developed AM, presenting an overall incidence of 0.75%. The mean time interval between surgery and first record of AM diagnosis was 2.57 ± 5.24 months (range, 0 day to 24 months). The incidence of AM was significantly higher in patients aged ≤ 40 years (21.28%) and those aged 40-50 years (3.32%), compared to those > 50 years (0.42%) (P < 0.001). AM developed much more frequently among patients with chronic angle-closure glaucoma (1.30%), compared to those with acute angle-closure glaucoma (0.32%, P < 0.001). Eleven eyes (0.37%) developed AM following non-filtering surgery compared to 24 eyes (2.27%) after filtering surgery (P < 0.001).

conclusionThe incidence of AM after glaucoma surgery was 0.75% in Chinese patients with primary angle closure glaucoma. Younger age, chronic angle-closure glaucoma, and undergoing filtering surgery, were identified as associated risk factors for developing AM. Phacoemulsification may have less risk of developing AM compared to filtering surgery.

Indexed as

Aqueous misdirectionGlaucoma surgeryIncidencePrimary angle-closure glaucoma

Identifiers

PMID37391810
PMCPMC10314601
OpenAlexW4382645620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.