ArticleNature communications2023
Longitudinal body mass index and cancer risk: a cohort study of 2.6 million Catalan adults.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Association Between Fat-Free Mass and Mortality: A Systematic Review and Meta-Analysis.Journal of cachexia, sarcopenia and muscle · 2026Pooled it
- GLP-1 receptor agonists and the risk for cancer: A meta-analysis of randomized controlled trials.Diabetes, obesity & metabolism · 2025 · on this mapPooled it
- Blood lipid metabolic biomarkers are emerging as significant prognostic indicators for survival in cancer patients.BMC cancer · 2024Pooled it
- Body mass index and dyslipidemia influence responses to anti-PD-1 immunotherapy in colorectal cancer.Annals of medicine · 2026Article
- Clinical obesity in Asian people: bridging the gap between adiposity and disease.Nature reviews. Endocrinology · 2026Review
- Comments on "Sensitive Period Analysis of Adulthood BMI and Cancer Risk: An Individual Participant Data Meta-Analysis of Over 720,000 Participants in the ABACus 2 Consortium".International journal of cancer · 2026Article
- The impact of cumulative obesity and genetic susceptibility on biological aging in Chinese older adults.GeroScience · 2026Article
- Article
- Interaction of serum resistin and smoking behavior in predicting depression risk: a sex-sensitive analysis.BMC psychiatry · 2026Article
- Citrate reduced gold nanoparticles lowered lipid content in differentiated 3T3-L1 adipocytes by altering the expression of adipogenic genes.Discover nano · 2026Article
- Longitudinal study of central obesity and glucose-lipid metabolism in predicting tumor remission among fertility-sparing endometrial cancer patients.European journal of obstetrics & gynecology and reproductive biology: X · 2026Article
- Development and Validation of a Chinese Obesity-Specific Physiological Database for PBPK Modeling.Clinical pharmacokinetics · 2026Article
- Effect of Hypoxic Exercise with Different Oxygen Concentrations on Metabolic Outcomes in Obesity: A Systematic Review and Network Meta-Analysis.Life (Basel, Switzerland) · 2026Review
- Glucagon-like peptide-1 medicines and cancer.Nature cancer · 2026Review
- Research Priorities and Future Directions in Cardio-Oncology.Current treatment options in oncology · 2026Review
- Clinical and Preclinical Obesity in Korean Adults from 2014 to 2023.Diabetes & metabolism journal · 2026Article
- Global, regional, and national burden of ovarian cancer due to high BMI, 1990-2021 and projections to 2050: a systematic analysis based on the global burden of disease 2021 study.Frontiers in nutrition · 2026Article
- Adolescent to adulthood weight trajectories and the risk of obesity-related cancers, overall and early-onset: a population-based cohort study.EClinicalMedicine · 2026Article
- Venous thromboembolism and 20-year cancer risk: a Danish population-based cohort study.Research and practice in thrombosis and haemostasis · 2026Article
- Breaking the obesity-cancer link: assessing European school-based and complementary obesity-prevention strategies and their implementation obstacles.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
Single body mass index (BMI) measurements have been associated with increased risk of 13 cancers. Whether life course adiposity-related exposures are more relevant cancer risk factors than baseline BMI (ie, at start of follow-up for disease outcome) remains unclear. We conducted a cohort study from 2009 until 2018 with population-based electronic health records in Catalonia, Spain. We included 2,645,885 individuals aged ≥40 years and free of cancer in 2009. After 9 years of follow-up, 225,396 participants were diagnosed with cancer. This study shows that longer duration, greater degree, and younger age of onset of overweight and obesity during early adulthood are positively associated with risk of 18 cancers, including leukemia, non-Hodgkin lymphoma, and among never-smokers, head and neck, and bladder cancers which are not yet considered as obesity-related cancers in the literature. Our findings support public health strategies for cancer prevention focussing on preventing and reducing early overweight and obesity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.