Evidence map›Paper›PMID 37391419›Full record

ReviewTranslational psychiatry2023

Machine learning in attention-deficit/hyperactivity disorder: new approaches toward understanding the neural mechanisms.

Meng Cao, Elizabeth Martin, Xiaobo Li

Abstract readReview
In one paragraph

Review in Translational psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meng CaoDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Elizabeth MartinIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Xiaobo LiDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA. xli.aecom@gmail.com.ORCID 0000-0002-8153-5415

Funding

General Brain Arousal and Risk for Eating DisorderR01MH126448 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HILDEBRANDT, THOMAS B, SCHULZ, KURT P. · 2021 to 2024
$1.7M
Neural Correlates of Familial and Non-familial ADHDR15MH117368 · NIMH · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI LI, XIAOBO · 2019 to 2019
$461k
Neuroanatomical markers of persistence versus remission of ADHDR03MH109791 · NIMH · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI LI, XIAOBO · 2016 to 2017
$154k
New Jersey Commission on Brain Injury Research (NJCBIR) CBIR17PIL012New Jersey Commission on Brain Injury Research (NJCBIR) CBIR22PIL002U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) R01MH126448U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) R03MH109791U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) R15MH117368
6 · The paper itself

Abstract

Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent and heterogeneous neurodevelopmental disorder in children and has a high chance of persisting in adulthood. The development of individualized, efficient, and reliable treatment strategies is limited by the lack of understanding of the underlying neural mechanisms. Diverging and inconsistent findings from existing studies suggest that ADHD may be simultaneously associated with multivariate factors across cognitive, genetic, and biological domains. Machine learning algorithms are more capable of detecting complex interactions between multiple variables than conventional statistical methods. Here we present a narrative review of the existing machine learning studies that have contributed to understanding mechanisms underlying ADHD with a focus on behavioral and neurocognitive problems, neurobiological measures including genetic data, structural magnetic resonance imaging (MRI), task-based and resting-state functional MRI (fMRI), electroencephalogram, and functional near-infrared spectroscopy, and prevention and treatment strategies. Implications of machine learning models in ADHD research are discussed. Although increasing evidence suggests that machine learning has potential in studying ADHD, extra precautions are still required when designing machine learning strategies considering the limitations of interpretability and generalization.

Indexed as

Attention Deficit Disorder with HyperactivityNeurodevelopmental DisordersAlgorithmsChildElectroencephalographyHumansMachine Learning

Identifiers

PMID37391419
PMCPMC10313824

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.