Evidence map›Paper›PMID 37391018›Full record

ReviewThe journal of allergy and clinical immunology. In practice2023

Recent Advances in the Treatment of Eosinophilic Esophagitis.

Amiko M Uchida, Caitlin M Burk, Marc E Rothenberg, Glenn T Furuta, Jonathan M Spergel

Open access · greenAbstract readReview
In one paragraph

Review in The journal of allergy and clinical immunology. In practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. The Past, the Present, and the Future of Periostin in Allergy.Allergy, asthma & immunology research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Amiko M UchidaDivision of Gastroenterology, Hepatology and Nutrition, University of Utah School of Medicine, Salt Lake City, Utah.
Caitlin M BurkFood Allergy Center and Division of Pediatric Allergy and Immunology, and Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Mass. Electronic address: cmburk@mgh.harvard.edu.
Marc E RothenbergDivision of Allergy and Immunology, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Glenn T FurutaDepartment of Pediatrics, Gastrointestinal Eosinophilic Diseases Program, University of Colorado School of Medicine, Digestive Health Institute, Children's Hospital Colorado, Aurora, Colo.
Jonathan M SpergelDivision of Allergy and Immunology, Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pa.
Children's Hospital Colorado · USMassachusetts General Hospital · USUniversity of Cincinnati Medical Center · USUniversity of Pennsylvania · USUniversity of Utah · US

Funding

TSLP, IL-9-producing mucosal mast cells, and allergic inflammationU19AI070235 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Gurjit K. Khurana Hershey · 2006 to 2026
$31.3M
TRAINING (CAREER DEVELOPMENT) COMPONENTU54AI117804 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI GLENN T FURUTA, Marc E. Rothenberg · 2014 to 2026
$18.5M
Research Training in Pulmonary Immunology and Allergy at MGHT32HL116275 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI David C Christiani, ANDREW D LUSTER · 2013 to 2026
$8.6M
Genetic and Immunological Dissection of Eosinophilic EsophagitisR01AI124355 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Marc E. Rothenberg · 2015 to 2026
$5.9M
REGULATION OF GASTROINTESTINAL EOSINOPHILSR01AI045898 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 1999 to 2024
$4.5M
Roles of FFAR 3-SCFA axis in Th2 cytokine production by tissuelymphocytes in EoER01AI148138 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2020 to 2024
$2.2M
Early life factors, gene-environment interaction and eosinophilic esophagitisR01AI139126 · NIAID · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI JENSEN, ELIZABETH T · 2018 to 2023
$1.7M
NHLBI NIH HHS T32 HL116275NIAID NIH HHS R01 AI045898NIAID NIH HHS R01 AI124355NIAID NIH HHS R01 AI139126NIAID NIH HHS R01 AI148138NIAID NIH HHS U19 AI070235NIAID NIH HHS U54 AI117804
6 · The paper itself

Abstract

Eosinophilic esophagitis is an increasingly common inflammatory allergic disease of the esophagus characterized by esophageal eosinophilia and symptoms of esophageal dysfunction. The therapeutic landscape has rapidly evolved for this emerging type 2 inflammatory disorder. We review traditional therapies including updates and expert opinions in addition to promising therapies on the horizon and the history of therapies that failed to meet end points and highlight knowledge gaps for future investigations.

Indexed as

Eosinophilic EsophagitisHumansAllergyEosinophilic esophagitisTreatmentUpdates

Identifiers

PMID37391018
PMCPMC10530275
OpenAlexW4382405089

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.