Evidence map›Paper›PMID 37389974›Full record

ArticleChannels (Austin, Tex.)2023

Secretory carrier-associated membrane protein 5 regulates cell-surface targeting of T-type calcium channels.

Emilio R Mustafá, Konstantin Weiß, Norbert Weiss

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Channels (Austin, Tex.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. The T-type calcium channelosome.Pflugers Archiv : European journal of physiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Emilio R MustafáDepartment of Pathophysiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic.ORCID 0000-0001-7480-558X
Konstantin WeißDepartment of Pathophysiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic.
Norbert WeissDepartment of Pathophysiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic.ORCID 0000-0002-0040-1109
Charles University · CZConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Missense mutations in the human secretary carrier-associated membrane protein 5 (SCAMP5) cause a variety of neurological disorders including neurodevelopmental delay, epilepsy, and Parkinson's disease. We recently documented the importance of SCAMP2 in the regulation of T-type calcium channel expression in the plasma membrane. Here, we show that similar to SCAMP2, the co-expression of SCAMP5 in tsA-201 cells expressing recombinant Ca

Indexed as

Calcium Channels, T-TypeCell MembraneDown-RegulationHumansMembrane ProteinsMutationCalcium Channels, T-TypeMembrane ProteinsSCAMP5 protein, humanCalcium channelsChannelopathyIon channelsSCAMP5Secretory carrier-associated membrane protein 5T-type channels

Identifiers

PMID37389974
PMCPMC10316736
OpenAlexW4382777138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.