ReviewMolecular diversity2024
Enantioselective organocatalytic Friedel-Crafts reaction of electron-rich phenols and isatins by Takemoto's thiourea catalyst.
Review in Molecular diversity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Takemoto's catalysts were used to organocatalyze the enantioselective Friedel-Crafts reaction with different electron-rich phenols and substituted isatins. The resulting 3-aryl-3-hydroxyl-2-oxindoles were obtained in good yields (85-96%) with up to 99% ee. The substrate scope was broadened with this methodology compared to reported examples catalyzed by cinchonidine thiourea.
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