Evidence map›Paper›PMID 37389748›Full record

ArticleActa neurochirurgica2023

Stem cell therapy for traumatic brachial plexus injury.

Ellen Y Lee, Robert J Spinner, Martin M Mortazavi, Diana Angius, Nimer Adeeb, Allen T Bishop, Alexander Y Shin

Open access · bronzeAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Trial
  2. Stem cell therapy for peripheral nerve injury: illustrative cases.Journal of neurosurgery. Case lessons · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Ellen Y LeeDepartment of Orthopedic Surgery, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.ORCID http://orcid.org/0000-0003-1175-7132
Robert J SpinnerDepartment of Neurosurgery, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
Martin M MortazaviCalifornia Institute of Neuroscience, 2100 Lynn Rd, Suite 120, Thousand Oaks, CA, 91360, USA.
Diana AngiusFondazione Don Gnocchi, Piazza Castello 20-22, 20060 Pessano con Bornago, Milan, Italy.
Nimer AdeebDepartment of Neurosurgery, Louisiana State University, Shreveport, LA, 71103, USA.
Allen T BishopDepartment of Orthopedic Surgery, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
Alexander Y ShinDepartment of Orthopedic Surgery, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA. shin.alexander@mayo.edu.
Mayo Clinic · USDon Carlo Gnocchi Foundation · ITLouisiana State University in Shreveport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cell therapy is rapidly evolving, with preclinical studies showing various stem cell types successfully promoting peripheral nerve regeneration. Despite the lack of clinical studies demonstrating efficacy and safety, the number of commercial entities marketing and promoting this treatment direct to patients is also increasing. We describe three adult traumatic brachial plexus injury (BPI) patients who had stem cell therapies prior to consultation in a multidisciplinary brachial plexus clinic. No functional improvement was noted at long-term follow-up despite claims reported by the commercial entities. Considerations and implications of stem cell application in BPI patients are reviewed.

Indexed as

Brachial PlexusBrachial Plexus NeuropathiesAdultHumansNerve RegenerationStem Cell TransplantationCell therapyRegenerative medicineStem cellsTraumatic brachial plexus injury

Identifiers

PMID37389748
OpenAlexW4382631168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.