Evidence map›Paper›PMID 37389710›Full record

ArticleJournal of fluorescence2024

Visible-light Excited and Highly Photostable Organic Fluorophore with dual-state Emission.

Yongchao Li, Liqing Zhang, Xianfeng Meng, Guowei Shi, Wei Gao, Guiyun Duan, Yanqing Ge

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Article in Journal of fluorescence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yongchao Li *Department of Chemistry and Pharmaceutical Engineering, Shandong First Medical University & Shandong Academy of Medical Sciences, No. 619, Changcheng Road, Taian, 271016, Shandong, China.
Liqing Zhang *Department of Chemistry and Pharmaceutical Engineering, Shandong First Medical University & Shandong Academy of Medical Sciences, No. 619, Changcheng Road, Taian, 271016, Shandong, China.
Xianfeng Meng *Department of Chemistry and Pharmaceutical Engineering, Shandong First Medical University & Shandong Academy of Medical Sciences, No. 619, Changcheng Road, Taian, 271016, Shandong, China.
Guowei ShiDepartment of Chemistry and Pharmaceutical Engineering, Shandong First Medical University & Shandong Academy of Medical Sciences, No. 619, Changcheng Road, Taian, 271016, Shandong, China.
Wei GaoDepartment of Chemistry and Pharmaceutical Engineering, Shandong First Medical University & Shandong Academy of Medical Sciences, No. 619, Changcheng Road, Taian, 271016, Shandong, China.
Guiyun DuanDepartment of Chemistry and Pharmaceutical Engineering, Shandong First Medical University & Shandong Academy of Medical Sciences, No. 619, Changcheng Road, Taian, 271016, Shandong, China. duanguiyun@126.com.
Yanqing GeDepartment of Chemistry and Pharmaceutical Engineering, Shandong First Medical University & Shandong Academy of Medical Sciences, No. 619, Changcheng Road, Taian, 271016, Shandong, China. geyanqing2016@126.com.

Funding

the Natural Science Foundation of Shandong Province ZR2021MB033
6 · The paper itself

Abstract

Organic fluorophores with dual-state emission (DSE) are rare or difficult to observe because most of them display either aggregation-induced emission (AIE) or aggregation-caused quenching (ACQ). Amazing works have been accomplished, yet most of the DSE compounds were excited by UV light which limits their wide application in bioimaging. In this work, we achieved a visible-light excited DSE fluorophore and realized its imaging in SKOV-3 cells and zebrafish. The naphtho[2',3':4,5]imidazo[1,2-a]pyridine (NIP) core ensures its emission in dilute solution. Meanwhile, the twisted phenyl ring blocks fluorescence quenching induced by the π-π stacking and leads to the emission of the solid. The fluorescence intensity is steady even after 6 h of continuous intense sunlight. More importantly, photostability of NIP in cells is much better than commercial dye (mitochondrial green).

Indexed as

Cell imagingDual-state emissionImidazo[1,2-a]pyridinePhotostabilityZebrafish

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.