Evidence map›Paper›PMID 37389688›Full record

ArticleWiener klinische Wochenschrift2024

Neuronal intranuclear inclusion disease with cortical involvement in left hemisphere: a case report.

Xiao-Ju Wu, Yi-Ying Jiang, Li-Jie Chen, Guo-Qiu Zhou, Dong-Can Mo, Liu-Yu Liu, Jian-Li Li, Xiao-Ling Li, Yu-Lan Tang, Man Luo

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Wiener klinische Wochenschrift, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiao-Ju WuDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China.
Yi-Ying JiangDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China.
Li-Jie ChenDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China.
Guo-Qiu ZhouDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China.
Dong-Can MoDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China.
Liu-Yu LiuDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China.
Jian-Li LiDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China.
Xiao-Ling LiDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China.
Yu-Lan TangDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China. tangyulan7@163.com.
Man LuoDepartment of Neurology, First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, China. luoman@gxmu.edu.cn.ORCID http://orcid.org/0000-0002-0543-9763
Guangxi Medical University · CN

Funding

Guangxi Medical and Health Appropriate Technology Development and Application Project S2022091National Natural Science Foundation of China 82260241Natural Science Foundation of Guangxi Province 2015GXNSFAA139171 and 2020GXNSFAA259053
6 · The paper itself

Abstract

backgroundNeuronal intranuclear inclusion disease (NIID) is a rare highly heterogeneous disease. In this paper, we present a case of NIID featured in cortical involvement in left hemisphere of brain and the imaging changes in the process of the disease. CASE PRESENTATION: A 57-year-old female was hospitalized due to recurrent attacks of headache with cognitive impairment and tremor for 2 years. The symptoms of headache episodes were reversible. The characteristic radiologic change was high intensity signal involving the grey matter-white matter junction on the brain diffusion-weighted imaging (DWI), which existed in the frontal lobe and then extended backwards. Atypical features on fluid-attenuated inversion recovery (FLAIR) sequences showing small patchy high signals in the cerebellar vermis. High signals and edema were detected on FLAIR images along the cortex of the left occipito-parieto-temporal lobes, expanding and gradually shrinking in the follow-up visit. Besides, cerebral atrophy and bilateral symmetrical leukoencephalopathy were also detected. Skin biopsy and genetic testing confirmed the diagnosis of NIID.

conclusionExcept for typical radiological change strongly suggesting NIID, it is also necessary to notice the insidious symptoms of NIID combining with some atypical imaging features to make an early diagnosis. Skin biopsies or genetic testing should be carried out early in patients with highly suspected NIID.

Indexed as

Neurodegenerative DiseasesDiffusion Magnetic Resonance ImagingFemaleHeadacheHumansIntranuclear Inclusion BodiesMagnetic Resonance ImagingMiddle AgedHeadacheIntranuclear inclusionMagnetic resonance imagingNOTCH2NLC geneTremor

Identifiers

PMID37389688
OpenAlexW4382632310

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.