Evidence map›Paper›PMID 37389665›Full record

ArticleJournal of biological physics2023

Analysis of SARS-CoV-2 interactions with the Vero cell lines by scanning electron microscopy.

Zuzana Malá, Marek Vojta, Jan Loskot, Radek Sleha, Bruno Ježek, Josef Zelenka

Abstract read
In one paragraph

Article in Journal of biological physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zuzana MaláDepartment of Physics, Faculty of Science, University of Hradec Králové, Rokitanského 62, Hradec Králové, 500 03, Czech Republic. zuzana.mala@uhk.cz.
Marek VojtaDepartment of Physics, Faculty of Science, University of Hradec Králové, Rokitanského 62, Hradec Králové, 500 03, Czech Republic.
Jan LoskotDepartment of Physics, Faculty of Science, University of Hradec Králové, Rokitanského 62, Hradec Králové, 500 03, Czech Republic.
Radek SlehaDepartment of Epidemiology, University of Defencein Brno, Třebešská, 1575, 500 02, Czech Republic.
Bruno JežekDepartment of Informatics and Quantitative Methods, University of Hradec Králové, Rokitanského 62, Hradec Králové, 500 03, Czech Republic.
Josef ZelenkaDepartment of Recreology and Tourism, University of Hradec Králové, Rokitanského 62, Hradec Králové, 500 03, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, scanning electron microscopy (SEM) was used to study the cell structure of SARS-CoV-2 infected cells. Our measurements revealed infection remodeling caused by infection, including the emergence of new specialized areas where viral morphogenesis occurs at the cell membrane. Intercellular extensions for viral cell surfing have also been observed. Our results expand knowledge of SARS-CoV-2 interactions with cells, its spread from cell to cell, and their size distribution. Our findings suggest that SEM is a useful microscopic method for intracellular ultrastructure analysis of cells exhibiting specific surface modifications that could also be applied to studying other important biological processes.

Indexed as

COVID-19SARS-CoV-2AnimalsCell LineChlorocebus aethiopsMicroscopy, Electron, ScanningVero CellsFilopodiaSARS-CoV-2Scanning electron microscopy (SEM)Surface morphologyVero cells

Identifiers

PMID37389665
PMCPMC10397163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.