Evidence map›Paper›PMID 37389644›Full record

ArticleWorld journal of surgery2023

Assessment of Machine Learning Methods to Predict Massive Blood Transfusion in Trauma.

Matt Strickland, Anthony Nguyen, Shinyi Wu, Sze-Chuan Suen, Yanda Mu, Juan Del Rio Cuervo, Brandon J Shin, Tej Kalakuntla, Cameron Ghafil, Kazuhide Matsushima

Open access · hybridAbstract read
In one paragraph

Article in World journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Title: Multimodal Fusion of Clinical and Imaging Data for Early Prediction of Massive Transfusion in Trauma.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026
    Article
  6. Article
  7. Utility of point of care viscoelastic haemostatic assays for trauma patients in the emergency department.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Observational
  8. Article
  9. Article
  10. Machine learning in the prediction of massive transfusion in trauma: a retrospective analysis as a proof-of-concept.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Matt Strickland *Department of Surgery, University of Southern California, LAC+USC Medical Center (The work was done at LAC+USC Medical Center), Los Angeles, CA, USA.
Anthony Nguyen *Daniel J. Epstein Department of Industrial and Systems Engineering, University of Southern California, Los Angeles, CA, USA.
Shinyi WuDaniel J. Epstein Department of Industrial and Systems Engineering, University of Southern California, Los Angeles, CA, USA.
Sze-Chuan SuenDaniel J. Epstein Department of Industrial and Systems Engineering, University of Southern California, Los Angeles, CA, USA.
Yanda MuDaniel J. Epstein Department of Industrial and Systems Engineering, University of Southern California, Los Angeles, CA, USA.
Juan Del Rio CuervoDaniel J. Epstein Department of Industrial and Systems Engineering, University of Southern California, Los Angeles, CA, USA.
Brandon J ShinDepartment of Surgery, University of Southern California, LAC+USC Medical Center (The work was done at LAC+USC Medical Center), Los Angeles, CA, USA.
Tej KalakuntlaDepartment of Surgery, University of Southern California, LAC+USC Medical Center (The work was done at LAC+USC Medical Center), Los Angeles, CA, USA.
Cameron GhafilDepartment of Surgery, University of Southern California, LAC+USC Medical Center (The work was done at LAC+USC Medical Center), Los Angeles, CA, USA.
Kazuhide MatsushimaDepartment of Surgery, University of Southern California, LAC+USC Medical Center (The work was done at LAC+USC Medical Center), Los Angeles, CA, USA. kazuhide.matsushima@med.usc.edu.ORCID 0000-0001-9625-5363
University of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurately predicting which patients are most likely to benefit from massive transfusion protocol (MTP) activation may help patients while saving blood products and limiting cost. The purpose of this study is to explore the use of modern machine learning (ML) methods to develop and validate a model that can accurately predict the need for massive blood transfusion (MBT).

methodsThe institutional trauma registry was used to identify all trauma team activation cases between June 2015 and August 2019. We used an ML framework to explore multiple ML methods including logistic regression with forward and backward selection, logistic regression with lasso and ridge regularization, support vector machines (SVM), decision tree, random forest, naive Bayes, XGBoost, AdaBoost, and neural networks. Each model was then assessed using sensitivity, specificity, positive predictive value, and negative predictive value. Model performance was compared to that of existing scores including the Assessment of Blood Consumption (ABC) and the Revised Assessment of Bleeding and Transfusion (RABT).

resultsA total of 2438 patients were included in the study, with 4.9% receiving MBT. All models besides decision tree and SVM attained an area under the curve (AUC) of above 0.75 (range: 0.75-0.83). Most of the ML models have higher sensitivity (0.55-0.83) than the ABC and RABT score (0.36 and 0.55, respectively) while maintaining comparable specificity (0.75-0.81; ABC 0.80 and RABT 0.83).

conclusionsOur ML models performed better than existing scores. Implementing an ML model in mobile computing devices or electronic health record has the potential to improve the usability.

Indexed as

Blood TransfusionHemorrhageBayes TheoremHumansMachine LearningPredictive Value of Tests

Identifiers

PMID37389644
PMCPMC10474168
OpenAlexW4382632064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.