Evidence map›Paper›PMID 37389488›Full record

ArticleAutophagy2023

The active zone protein CLA-1 (Clarinet) bridges two subsynaptic domains to regulate presynaptic sorting of ATG-9.

Zhao Xuan, Daniel A Colón-Ramos

Abstract read
In one paragraph

Article in Autophagy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhao XuanSchool of Biology and Ecology, University of Maine, Orono, ME, USA.ORCID 0000-0002-8254-2887
Daniel A Colón-RamosProgram in Cellular Neuroscience, Neurodegeneration and Repair, Departments of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, CT, USA.

Funding

Powering the Brain: the Cell Biology of NeuroenergeticsDP1NS111778 · NINDS · YALE UNIVERSITY · PI COLON-RAMOS, DANIEL A · 2018 to 2022
$5.9M
Cellular and molecular mechanisms that temporally and spatially restrict synapticR01NS076558 · NINDS · YALE UNIVERSITY · PI COLON-RAMOS, DANIEL A · 2012 to 2022
$4.1M
Howard Hughes Medical Institute 55108513NINDS NIH HHS DP1 NS111778NINDS NIH HHS R01 NS076558
6 · The paper itself

Abstract

In neuronal synapses, autophagosome biogenesis is coupled with the activity-dependent synaptic vesicle cycle via ATG-9. How vesicles containing ATG-9 are sorted at the presynapse is unknown. We performed forward genetic screens at single synapses of

Indexed as

AutophagyCaenorhabditis elegansAnimalsAutophagy-Related ProteinsCaenorhabditis elegans ProteinsCarrier ProteinsMembrane ProteinsPresynaptic TerminalsSynapsesSynaptic Vesiclesatg-9 protein, C elegansAutophagy-Related ProteinsCaenorhabditis elegans ProteinsCarrier ProteinsMembrane Proteinsactive zoneadaptor protein complexesATG-9CLA-1periactive zonesynaptic vesicle cyclesyndapin 1

Identifiers

PMID37389488
PMCPMC10472863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.