Evidence map›Paper›PMID 37389318›Full record

ArticleSafety and health at work2023

Occupational Exposure during Intraperitoneal Pressurized Aerosol Chemotherapy Using Doxorubicin in a Pig Model.

Wongeon Jung, Mijin Park, Soo Jin Park, Eun Ji Lee, Hee Seung Kim, Sun Ho Chung, Chungsik Yoon

Abstract read
In one paragraph

Article in Safety and health at work, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wongeon JungDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Mijin ParkDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Soo Jin ParkDepartment of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
Eun Ji LeeDepartment of Obstetrics and Gynecology, Chung-Ang University Hospital, Seoul, Republic of Korea.
Hee Seung KimDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Sun Ho ChungBio-Center, Gyeonggido Business & Science Accelerator (GBSA), Suwon, Republic of Korea.
Chungsik YoonDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study evaluated occupational exposure levels of doxorubicin in healthcare workers performing rotational intraperitoneal pressurized aerosol chemotherapy (PIPAC) procedures. Methods: All samples were collected during PIPAC procedures applying doxorubicin to an experimental animal model (pigs). All procedures were applied to seven pigs, each for approximately 44 min. Surface samples ( Results: Among the surface samples, doxorubicin was detected in only five samples (9.8%) that were directly exposed to antineoplastic drug aerosols in the abdominal cavity originating from PIPAC devices. The telescopes showed concentrations of 0.48-5.44 ng/cm Conclusions: Most air and surface samples were uncontaminated or showed very low doxorubicin concentrations during PIPAC procedures. However, there remains a potential for leakage, in which case dermal exposure may occur. Safety protocols related to leakage accidents, selection of appropriate protective equipment, and the use of disposable devices are necessary to prevent occupational exposure.

Indexed as

DoxorubicinOccupational exposurePIPACPressurized intraperitoneal aerosol chemotherapy

Identifiers

PMID37389318
PMCPMC10300457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.