Evidence map›Paper›PMID 37389231›Full record

ArticleWorld journal of gastroenterology2023

Pre-transjugular-intrahepatic-portosystemic-shunt measurement of hepatic venous pressure gradient and its clinical application: A comparison study.

Xi-Xuan Wang, Xiao-Chun Yin, Li-Hong Gu, Hui-Wen Guo, Yang Cheng, Yan Liu, Jiang-Qiang Xiao, Yi Wang, Wei Zhang, Xiao-Ping Zou and 4 more

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xi-Xuan WangDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Xiao-Chun YinDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Li-Hong GuDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Hui-Wen GuoDepartment of Gastroenterology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu Province, China.
Yang ChengDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Yan LiuDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Jiang-Qiang XiaoDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Yi WangDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Wei ZhangDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Xiao-Ping ZouDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Lei WangDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Ming ZhangDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Yu-Zheng Zhu-GeDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China.
Feng ZhangDepartment of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, Jiangsu Province, China. fzdndx@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is controversial whether transjugular intrahepatic portosystemic shunt (TIPS) placement can improve long-term survival.

aimTo assess whether TIPS placement improves survival in patients with hepatic-venous-pressure-gradient (HVPG) ≥ 16 mmHg, based on HVPG-related risk stratification.

methodsConsecutive variceal bleeding patients treated with endoscopic therapy + nonselective β-blockers (NSBBs) or covered TIPS placement were retrospectively enrolled between January 2013 and December 2019. HVPG measurements were performed before therapy. The primary outcome was transplant-free survival; secondary endpoints were rebleeding and overt hepatic encephalopathy (OHE).

resultsA total of 184 patients were analyzed (mean age, 55.27 years ± 13.86, 107 males; 102 in the EVL+NSBB group, 82 in the covered TIPS group). Based on the HVPG-guided risk stratification, 70 patients had HVPG < 16 mmHg, and 114 patients had HVPG ≥ 16 mmHg. The median follow-up time of the cohort was 49.5 mo. There was no significant difference in transplant-free survival between the two treatment groups overall (hazard ratio [HR], 0.61; 95% confidence interval [CI]: 0.35-1.05;

conclusionTIPS placement can effectively improve transplant-free survival when the HVPG is greater than 16 mmHg.

Indexed as

Esophageal and Gastric VaricesHepatic EncephalopathyGastrointestinal HemorrhageGraft SurvivalHumansMaleMiddle AgedPortal PressureRetrospective StudiesCirrhosisHepatic venous pressure gradientSurvivalTransjugular intrahepatic portosystemic shuntsVariceal rebleeding

Identifiers

PMID37389231
PMCPMC10303515

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.