ArticleFrontiers in cellular and infection microbiology2023
The outer membrane proteins based seroprevalence strategy for
Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Application of Outer Membrane Protein Omp25 in Serological Diagnosis of Brucellosis.Infectious disease reports · 2026Review
- Seasonal dynamic modeling for real-time prediction of human brucellosis epidemiological trends in Gansu, Guangdong and Sichuan Provinces, China.PLoS neglected tropical diseases · 2026Article
- Development and preliminary validation of anFrontiers in microbiology · 2026Article
- Optimizing ovine brucellosis serodiagnosis: evaluation of recombinantFrontiers in veterinary science · 2026Article
- Development and evaluation of novel Brucella diagnostic antigen protein ST.BMC infectious diseases · 2025Article
- The Potential of a CT-Based Machine Learning Radiomics Analysis to Differentiate Brucella and Pyogenic Spondylitis.Journal of inflammation research · 2023Article
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Authors and funding
8 authors.
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Abstract
Introduction: The diagnosis of brucellosis largely relies on tiger red plate agglutination test (RBPT). However, it is difficult to distinguish between natural infection antibody positive and vaccination antibody positive, nevertheless, the identification of specific Brucella species natural infection. Methods: Here, we analyzed the structure of main outer membrane proteins (OMPs), OMP25 and OMP31 from Results: They have equally efficiency in antibody detection of vaccinated sheep serum, consistent with the RBPT results. However, through epidemiological investigations, we found some RBPT positive samples were negative by the OMP31m based serum antibody detection, but these samples gave positive results by the OMP25o. We verified these OMP31m negative but OMP25o positive samples by Discussion: Currently, China has not yet approved a vaccine based on
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