ArticleWorld journal of gastrointestinal oncology2023
Chicken skin mucosa surrounding small colorectal cancer could be an endoscopic predictive marker of submucosal invasion.
Article in World journal of gastrointestinal oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Characteristics of small early colorectal cancer in the non-pedunculated lesions and its relationship with the depth of invasion.BMC gastroenterology · 2026Article
- White spots around colorectal tumors are cancer-related findings and may aid endoscopic diagnosis: a prospective study in Japan.Clinical endoscopy · 2024Article
- Mucosa color and size may indicate malignant transformation of chicken skin mucosa-positive colorectal neoplastic polyps.World journal of gastrointestinal oncology · 2024Article
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8 authors.
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Abstract
backgroundChicken skin mucosa (CSM) surrounding colon polyps is a common endoscopic finding with pale yellow-speckled mucosa during a colonoscopy screening. Although reports about CSM surrounding small colorectal cancer are scarce, and its clinical significance in intramucosal and submucosal cancers is unclear, previous studies have suggested it could be an endoscopic predictive marker for colonic neoplastic and advanced polyps. Currently, because of the inaccurate preoperative evaluation by endoscopists, many small colorectal cancers, particularly lesions with a diameter < 2 cm, are improperly treated. Therefore, more effective methods are required to better assess the depth of the lesion before treatment.
aimTo explore potential markers of small colorectal cancer early invasion under white light endoscopy, providing patients with better treatment alternatives.
methodsThis retrospective cross-sectional study included 198 consecutive patients [233 early colorectal cancers (ECCs)] who underwent endoscopy or surgical procedures at the Digestive Endoscopy Center of Chengdu Second People's Hospital between January 2021 and August 2022. The participants had pathologically confirmed colorectal cancer with a lesion diameter < 2 cm and received endoscopic or surgical treatment, including endoscopic mucosal resection and submucosal dissection. Clinical pathology and endoscopy parameters, including tumor size, invasion depth, anatomical position, and morphology, were reviewed. Fisher's exact test, the
resultsThe submucosal carcinoma (SM stage) was larger than the mucosal carcinoma (M stage) with a significant difference (17.2 ± 4.1
conclusionCSM-related small colorectal cancer was primarily located in the left colon and could be a predictive marker of submucosal invasion in the left colon.
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