Evidence map›Paper›PMID 37388918›Full record

ArticleCell genomics2023

Proteomics of immune cells from liver tumors reveals immunotherapy targets.

Fernando P Canale, Julia Neumann, Janusz von Renesse, Elisabetta Loggi, Matteo Pecoraro, Ian Vogel, Giada Zoppi, Gaia Antonini, Tobias Wolf, Wenjie Jin and 20 more

Abstract read
In one paragraph

Article in Cell genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. TIGITCancers · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Translational Downregulation of 5' TOP mRNAs During T Cell Exhaustion.bioRxiv : the preprint server for biology · 2025
    Article
  7. Blocking CXCR4Genome medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. X and Y Differences in Melanoma Survival Between the Sexes.Pigment cell & melanoma research · 2025
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Fernando P CanaleInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.
Julia NeumannInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.
Janusz von RenesseDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Elisabetta LoggiHepatology Unit, Department of Medical & Surgical Sciences, University of Bologna, Bologna, Italy.
Matteo PecoraroInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.
Ian VogelInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.
Giada ZoppiInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.
Gaia AntoniniInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.
Tobias WolfInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.
Wenjie JinInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.
Xiaoqin ZhengInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.
Giuliano La BarbaGeneral and Oncologic Surgery, Morgagni-Pierantoni Hospital, Forlì, Italy.
Emrullah BirginDepartment of Surgery, Medical Faculty Mannheim, Universitätsmedizin Mannheim, Heidelberg University, Mannheim, Germany.
Marianne ForkelRoche Pharma Research and Early Development, Infectious Diseases Discovery, Roche Innovation Center Basel, Basel, Switzerland.
Tobias NilssonRoche Pharma Research and Early Development, Infectious Diseases Discovery, Roche Innovation Center Basel, Basel, Switzerland.
Romina MaroneDepartment of Biomedicine, University of Basel, Basel, Switzerland.
Henrik MuellerRoche Pharma Research and Early Development, Infectious Diseases Discovery, Roche Innovation Center Basel, Basel, Switzerland.
Nadege PelletierRoche Pharma Research and Early Development, Infectious Diseases Discovery, Roche Innovation Center Basel, Basel, Switzerland.
Lukas T JekerDepartment of Biomedicine, University of Basel, Basel, Switzerland.
Gianluca CivenniUniversità della Svizzera italiana (USI), Lugano, Switzerland.
Christoph SchlapbachDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Carlo V CatapanoUniversità della Svizzera italiana (USI), Lugano, Switzerland.
Lena SeifertDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Adrian M SeifertDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Silke GillessenUniversità della Svizzera italiana (USI), Lugano, Switzerland.
Sara De DossoUniversità della Svizzera italiana (USI), Lugano, Switzerland.
Alessandra CristaudiDepartment of General and Visceral Surgery, Cantonal Hospital Lugano, Lugano, Switzerland.
Nuh N RahbariDepartment of Surgery, Medical Faculty Mannheim, Universitätsmedizin Mannheim, Heidelberg University, Mannheim, Germany.
Giorgio ErcolaniDepartment of Medical and Surgical Sciences - DIMEC; Alma Mater Studiorum - Univeristy of Bologna, Bologna, Italy.
Roger GeigerInstitute for Research in Biomedicine (IRB), Bellinzona, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elucidating the mechanisms by which immune cells become dysfunctional in tumors is critical to developing next-generation immunotherapies. We profiled proteomes of cancer tissue as well as monocyte/macrophages, CD4

Indexed as

cancer immunotherapyCRISPR in mouse T cellsHCCliver cancermacrophagesmass spectrometry-based proteomicsNK cellsprofiles of tumor-infiltrating immune cellsproteomesT cells

Identifiers

PMID37388918
PMCPMC10300607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.