Evidence map›Paper›PMID 37388786›Full record

ArticleWorld journal of clinical cases2023

Anti-bacterial mechanism of baicalin-tobramycin combination on carbapenem-resistant

Li-Min Jin, Hui Shen, Xing-Ying Che, Ye Jin, Chun-Mei Yuan, Neng-Hua Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Sub-inhibitory tobramycin concentration suppresses ToxA and LipA in single- and dual-species biofilms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Li-Min JinLaboratory Department, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing 314001, Zhejiang Province, China.
Hui ShenLaboratory Department, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing 314001, Zhejiang Province, China.
Xing-Ying CheLaboratory Department, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing 314001, Zhejiang Province, China.
Ye JinLaboratory Department, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing 314001, Zhejiang Province, China.
Chun-Mei YuanLaboratory Department, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing 314001, Zhejiang Province, China.
Neng-Hua ZhangLaboratory Department, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing 314001, Zhejiang Province, China. znhshzyxwx@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

aimTo investigate the effectiveness of baicalin combined with tobramycin therapy as a potential treatment method for carbapenem-resistant

methodsPolymerase chain reaction (PCR) and RT-PCR were used to detect the expression levels of drug-resistant genes (including

resultsThere was a correlation between biofilm formation and the expression of biofilm-related genes. In addition,

conclusionBaicalin combined with tobramycin therapy can be an effective treatment method for patients with CRPA infection.

Indexed as

BaicalinCarbapenem-resistant Pseudomonas aeruginosaPseudomonas aeruginosaTherapyTobramycin

Identifiers

PMID37388786
PMCPMC10303599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.