Evidence map›Paper›PMID 37388733›Full record

ArticleFrontiers in immunology2023

Phosphorylated STAT3 as a potential diagnostic and predictive biomarker in ALK

Chenxi Xiang, Wanna Wu, Meiting Fan, Zhen Wang, Xiaoli Feng, Cuiling Liu, Jia Liu, Guangzhen Liu, Lei Xia, Haipeng Si and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Chenxi XiangDepartment of Pathology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Wanna WuDepartment of Pathology, The First Affiliated Hospital and School of Clinical Medicine of Guangdong Pharmaceutical University, Guangzhou, China.
Meiting FanDepartment of Pathology, Xuzhou Medical University, Xuzhou, China.
Zhen WangDepartment of Pathology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaoli FengDepartment of Pathology, National Cancer Center and National Clinical Research Center For Cancer and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Cuiling LiuDepartment of Pathology, School of Basic Medical Sciences and Third Hospital, Pekin University Health Science Center, Beijing, China.
Jia LiuDepartment of Pathology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Guangzhen LiuDepartment of Pathology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Lei XiaDepartment of Pathology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Haipeng SiDepartment of Pathology, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Ying GuDepartment of Pathology, Xuzhou Medical University, Xuzhou, China.
Nian LiuDepartment of Pathology, Xuzhou Medical University, Xuzhou, China.
Dan LuoDepartment of Pathology, Xuzhou Medical University, Xuzhou, China.
Yubo WangDepartment of Pathology, Xuzhou Medical University, Xuzhou, China.
Dongshen MaDepartment of Pathology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Shimin HuDepartment of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Hui LiuDepartment of Pathology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Xuzhou Medical College · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNGuangdong Pharmaceutical University · CNNanjing Medical University · CNNanjing University of Chinese Medicine · CNThe University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The differential diagnosis between ALK-negative anaplastic large cell lymphoma (ALK Methods: The status of phosphorylation of STAT3 was examined using two antibodies against pSTAT3-Y705 and pSTAT3-S727 by immunohistochemistry in ALK Results: The median H-scores of pSTAT3-Y705 and S727 were 280 and 260 in ALK Conclusions: pSTAT3-Y705/S727 can be used to help distinguish ALK

Indexed as

Lymphoma, T-Cell, PeripheralAntibodiesBiomarkersHumansLymphocytes, Tumor-InfiltratingReceptor Protein-Tyrosine KinasesSTAT3 Transcription FactorAntibodiesBiomarkersReceptor Protein-Tyrosine KinasesSTAT3 protein, humanSTAT3 Transcription Factoranaplastic large cell lymphomaCD30not otherwise specifiedperiphearal T cell lymphomapSTAT3

Identifiers

PMID37388733
PMCPMC10303105
OpenAlexW4380682665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.