Evidence map›Paper›PMID 37388687›Full record

ArticleJACS Au2023

Direct Observation of Membrane-Associated H-Ras in the Native Cellular Environment by In-Cell

Masaomi Ikari, Hiromasa Yagi, Takuma Kasai, Kohsuke Inomata, Masahiro Ito, Kae Higuchi, Natsuko Matsuda, Yutaka Ito, Takanori Kigawa

Abstract read
In one paragraph

Article in JACS Au, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Masaomi IkariRIKEN Center for Biosystems Dynamics Research, Kanagawa 230-0045, Japan.
Hiromasa YagiRIKEN Center for Biosystems Dynamics Research, Kanagawa 230-0045, Japan.ORCID https://orcid.org/0000-0001-8059-4440
Takuma KasaiRIKEN Center for Biosystems Dynamics Research, Kanagawa 230-0045, Japan.
Kohsuke InomataRIKEN Center for Biosystems Dynamics Research, Kanagawa 230-0045, Japan.
Masahiro ItoRIKEN Center for Biosystems Dynamics Research, Kanagawa 230-0045, Japan.
Kae HiguchiRIKEN Center for Biosystems Dynamics Research, Kanagawa 230-0045, Japan.
Natsuko MatsudaRIKEN Center for Biosystems Dynamics Research, Kanagawa 230-0045, Japan.
Yutaka ItoDepartment of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Tokyo 192-0397, Japan.
Takanori KigawaRIKEN Center for Biosystems Dynamics Research, Kanagawa 230-0045, Japan.ORCID https://orcid.org/0000-0003-0146-9719

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ras acts as a molecular switch to control intracellular signaling on the plasma membrane (PM). Elucidating how Ras associates with PM in the native cellular environment is crucial for understanding its control mechanism. Here, we used in-cell nuclear magnetic resonance (NMR) spectroscopy combined with site-specific

Identifiers

PMID37388687
PMCPMC10302746

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.