Evidence map›Paper›PMID 37388575›Full record

ArticleJournal of the Endocrine Society2023

Trends in Management of Osteoporosis Following Primary Vertebral Compression Fracture.

Karen Malacon, Isidora Beach, Gavin Touponse, Taiyeb Rangwalla, Jennifer Lee, Corinna Zygourakis

Abstract read
In one paragraph

Article in Journal of the Endocrine Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Impact of the guidance on fracture Liaison Services and the introduction of a new fee for secondary fracture prevention in Japan: Implementation of secondary fracture prevention during hospitalization for fragility fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Karen MalaconSchool of Medicine, Stanford University Medical Center, Stanford, CA 94305, USA.ORCID https://orcid.org/0000-0002-4782-0466
Isidora BeachDepartment of Neurosurgery, Larner College of Medicine at The University of Vermont, Burlington, VT 05405, USA.ORCID https://orcid.org/0000-0003-0739-2329
Gavin TouponseSchool of Medicine, Stanford University Medical Center, Stanford, CA 94305, USA.ORCID https://orcid.org/0000-0001-8087-3351
Taiyeb RangwallaDepartment of Neurosurgery, Dell Medical School, The University of Texas at Austin, Austin, TX 78712, USA.
Jennifer LeeDepartment of Medicine, Stanford University Medical Center, Stanford, CA 94305, USA.
Corinna ZygourakisDepartment of Neurosurgery, Stanford University Medical Center, Stanford, CA 94305, USA.ORCID https://orcid.org/0000-0002-1894-9252

Funding

Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
NCATS NIH HHS UL1 TR003142
6 · The paper itself

Abstract

Purpose: Osteoporosis affects more than 200 million individuals worldwide and predisposes to vertebral compression fractures (VCFs). Given undertreatment of fragility fractures, including VCFs, we investigate current anti-osteoporotic medication prescribing trends. Methods: Patients 50 and older with a diagnosis of primary closed thoracolumbar VCF between 2004 and 2019 were identified from the Clinformatics® Data Mart database. Multivariate analysis was performed for demographic and clinical treatment and outcome variables. Results: Of 143 081 patients with primary VCFs, 16 780 (11.7%) were started on anti-osteoporotic medication within a year; 126 301 (88.3%) patients were not started on medication. The medication cohort was older (75.4 ± 9.3 vs 74.0 ± 12.3 years, Conclusions: Osteoporosis remains undertreated after low-energy VCFs. New anti-osteoporotic medication classes have been approved in recent years. Bisphosphonates remain the most prescribed class. Increasing recognition and treatment of osteoporosis is paramount to decreasing the risk of subsequent fractures.

Indexed as

medicationosteoporosistrendsvertebral compression fracture

Identifiers

PMID37388575
PMCPMC10306270

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.