Evidence map›Paper›PMID 37388528›Full record

ArticleRadiology case reports2023

Ectopic pituitary neuroendocrine tumor arising in the sphenoid sinus with an avid 18F-fluorodeoxyglucose uptake masquerading as malignancy: A case report.

Yukiko Usui, Ryo Kurokawa, Takahiro Fukushima, Richi Fujita, Reina Hosoi, Emi Miyawaki, Michio Hayashi, Sadahiro Kishisita, Mariko Kurokawa, Osamu Abe and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yukiko UsuiDepartment of Radiology, NTT Medical Center Tokyo, Shinagawa-ku, Tokyo, Japan.
Ryo KurokawaDepartment of Radiology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Takahiro FukushimaDepartment of Radiology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Richi FujitaDepartment of Radiology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Reina HosoiDepartment of Radiology, NTT Medical Center Tokyo, Shinagawa-ku, Tokyo, Japan.
Emi MiyawakiDepartment of Radiology, NTT Medical Center Tokyo, Shinagawa-ku, Tokyo, Japan.
Michio HayashiDepartment of Diabetes and Endocrinology, NTT Medical Center Tokyo, Shinagawa-ku, Tokyo, Japan.
Sadahiro KishisitaDepartment of Otorhinolaryngology-Head and Neck Surgery, NTT Medical Center Tokyo, Shinagawa-ku, Tokyo, Japan.
Mariko KurokawaDepartment of Radiology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Osamu AbeDepartment of Radiology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Haruyasu YamadaDepartment of Radiology, NTT Medical Center Tokyo, Shinagawa-ku, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ectopic pituitary neuroendocrine tumors (PitNETs) are uncommon conditions that develop outside of the sella turcica. The sphenoid sinus is the most common site for ectopic PitNET, followed by the suprasellar region, clivus, and cavernous sinus. PitNETs, regardless of whether inside or outside sella, may display avid 18F-fluorodeoxyglucose (FDG) uptake and masquerade as malignant tumors. Herein, we report a case of ectopic PitNET arising in the sphenoid sinus, which was found as an FDG-avid mass during cancer screening. On magnetic resonance imaging, the tumor showed heterogeneous and intermediate signal intensity areas on T1- and T2-weighted images with cystic components, which was consistent with PitNET. The localization and the presence of empty sella were suggestive of ectopic PitNET, and the diagnosis of ectopic PitNET (prolactinoma) was confirmed by endoscopic biopsy. Ectopic PitNET should be considered in a mass similar in nature to an orthogonal PitNET in areas near the sella turcica especially in patients with empty sella.

Indexed as

18F-FDG PET/CT18F-fluorodeoxyglucose uptakeEctopic PitNETEctopic pituitary adenomaSphenoid sinus

Identifiers

PMID37388528
PMCPMC10300046

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