Evidence map›Paper›PMID 37387784›Full record

ArticleFrontiers in medicine2023

A group of three miRNAs can act as candidate circulating biomarkers in liquid biopsies from melanoma patients.

Eleonora De Martino, Ilaria Gandin, Eros Azzalini, Cesare Massone, Maria Antonietta Pizzichetta, Erika Giulioni, Sanja Javor, Caterina Pinzani, Claudio Conforti, Iris Zalaudek and 1 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Omics in Cutaneous Melanoma.Asian Pacific journal of cancer prevention : APJCP · 2025
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eleonora De MartinoDermatology and Venerology Unit, Department of Medical Sciences, University of Trieste, Trieste, Italy.
Ilaria GandinBiostatistics Unit, Department of Medical Sciences, University of Trieste, Trieste, Italy.
Eros AzzaliniDermatology and Venerology Unit, Department of Medical Sciences, University of Trieste, Trieste, Italy.
Cesare MassoneDermatology Unit and Scientific Directorate, Ospedali Galliera, Genova, Italy.
Maria Antonietta PizzichettaDermatology and Venerology Unit, Department of Medical Sciences, University of Trieste, Trieste, Italy.
Erika GiulioniDermatology Unit, AS FO Azienda sanitaria Friuli Occidentale, Pordenone, Italy.
Sanja JavorDermatology Unit, Ospedali Galliera, Genova, Italy.
Caterina PinzaniOncologic Dermatology Prevention Unit, Centro di Riferimento Oncologico (CRO), IRCCS, Aviano, Italy.
Claudio ConfortiDermatology and Venerology Unit, Department of Medical Sciences, University of Trieste, Trieste, Italy.
Iris ZalaudekDermatology and Venerology Unit, Department of Medical Sciences, University of Trieste, Trieste, Italy.
Serena BoninDermatology and Venerology Unit, Department of Medical Sciences, University of Trieste, Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Staging of melanoma and follow up after melanoma diagnosis aims at predicting risk and detecting progression or recurrence at early stage, respectively in order to timely start and/or change treatment. Tumor thickness according to Breslow, status of the sentinel node and value of the lactate dehydrogenase (LDH) are well-established prognostic markers for metastatic risk, but reliable biomarkers identifying early recurrence or candidates who may benefit best from medical treatment are still warranted. Liquid biopsy has emerged to be a suitable method for identifying biomarkers for early cancer diagnosis, prognosis, therapeutic response prediction, and patient follow-up. Liquid biopsy is a blood-based non-invasive procedure that allows analyzing circulating analytes, including extracellular vesicles. Methods: In this study we have explored the use of 7 miRNAs, namely Results and discussion: Our results showed that three out seven miRNAs, namely

Indexed as

exosomesliquid biopsymelanomamiRNAplasma

Identifiers

PMID37387784
PMCPMC10301821

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.