Evidence map›Paper›PMID 37387446›Full record

ArticleInternational journal of oncology2023

RPL27 contributes to colorectal cancer proliferation and stemness via PLK1 signaling.

So-Young Park, Daekwan Seo, Eun-Hye Jeon, Jee Young Park, Byeong-Churl Jang, Jee In Kim, Seung-Soon Im, Jae-Ho Lee, Shin Kim, Chi Heum Cho and 1 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Experimental and therapeutic medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

So-Young ParkDepartment of Molecular Medicine, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Daekwan SeoDepartment of Bioinformatics, Psomagen Inc., Rockville, MD 20850, USA.
Eun-Hye JeonDepartment of Molecular Medicine, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Jee Young ParkDepartment of Immunology, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Byeong-Churl JangDepartment of Molecular Medicine, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Jee In KimDepartment of Molecular Medicine, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Seung-Soon ImDepartment of Physiology, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Jae-Ho LeeDepartment of Anatomy, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Shin KimDepartment of Immunology, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Chi Heum ChoDepartment of Obstetrics and Gynecology, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Yun-Han LeeDepartment of Molecular Medicine, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
Keimyung University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although expression of ribosomal protein L27 (RPL27) is upregulated in clinical colorectal cancer (CRC) tissue, to the best of our knowledge, the oncogenic role of RPL27 has not yet been defined. The present study aimed to investigate whether targeting RPL27 could alter CRC progression and determine whether RPL27 gains an extra‑ribosomal function during CRC development. Human CRC cell lines HCT116 and HT29 were transfected with RPL27‑specific small interfering RNA and proliferation was assessed

Indexed as

Colorectal NeoplasmsProtein Serine-Threonine KinasesAnimalsHumansMiceMice, NudePolo-Like Kinase 1Ribosomal ProteinsPolo-Like Kinase 1Protein Serine-Threonine KinasesRibosomal Proteinsribosomal proteins L27colorectal cancerextra‑ribosomal functionpolo‑like kinase 1ribosomal protein L27stemnesstumor progression

Identifiers

PMID37387446
PMCPMC10552708
OpenAlexW4382631466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.