ArticleJournal of veterinary internal medicine
Comparison of cystocentesis versus home sampling to determine urinary protein: Creatinine ratio and urine specific gravity in cats.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 8 citations in OpenAlex.
- Longitudinal evaluation of discordant symmetric dimethylarginine and creatinine as markers of glomerular filtration rate in radioiodine-treated hyperthyroid cats.Journal of feline medicine and surgery · 2026Article
- SGLT2 inhibitor therapy in diabetic cats: first clinical experiences with non-ideal candidates.Journal of feline medicine and surgery · 2026Article
- Exposure of urine of domestic cats to different substrates: impact on urine specific gravity.Journal of feline medicine and surgery · 2025Article
- Urinary protein-to-creatinine ratio in guinea pigs (Cavia porcellus): Reference range and the effect of age and sex.The Veterinary record · 2024Article
- Age-related trends in urine specific gravity in apparently healthy cats.Journal of feline medicine and surgery · 2024Article
- Comparison of cystocentesis versus home sampling to determine urinary protein: Creatinine ratio and urine specific gravity in cats.Journal of veterinary internal medicineArticle
- Value of repeated health screening in 259 apparently healthy mature adult and senior cats followed for 2 years.Journal of veterinary internal medicineArticle
- Biological variation of urinary protein: Creatinine ratio and urine specific gravity in cats.Journal of veterinary internal medicineArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundUrinalysis is necessary for the diagnostic evaluation of chronic kidney disease in cats. Performing cystocentesis is not always feasible, but data comparing urine obtained by cystocentesis in the clinic with voided samples collected at home are lacking in cats.
objectivesTo compare urinary protein:creatinine ratio (UPC) and urine specific gravity (USG) and to detect clinically relevant changes in proteinuria substage or urine concentration between urine collected at home and in-clinic by cystocentesis in cats. ANIMALS: Ninety-two healthy and diseased client-owned cats.
methodsProspective study. Owners collected voided urine at home and within 1 to 15 hours, cystocentesis was performed in the clinic.
resultsIn a subset of motivated owners, 55% succeeded in collecting urine at home. Overall, UPC was higher (mean ±SD difference = 0.09 ±0.22; P < .001) and USG was lower (mean ±SD difference = -0.006 ±0.009; P < .001) in cystocentesis samples than in voided urine. Substantial agreement existed between sampling methods for UPC (weighted к = 0.68) and USG (к = 0.64) categories. A different proteinuria substage (UPC < 0.2, 0.2-0.4, >0.4) was present in paired urine samples from 28% of cats. In 18% of cats, urine concentrating ability (USG < or ≥1.035) differed between both samples. CONCLUSIONS AND CLINICAL IMPORTANCE: Home sampling of urine is a valid alternative to cystocentesis in cats. However, because clinically relevant differences in UPC and USG were present in 28% and 18% of cats, respectively, by the same collection method for monitoring each cat is advised.
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