Evidence map›Paper›PMID 37387311›Full record

ArticleChemical communications (Cambridge, England)2023

Rapid post-synthetic modification of porous coordination cages with copper-catalyzed click chemistry.

Michael R Dworzak, Christine M Montone, Nicole I Halaszynski, Glenn P A Yap, Christopher J Kloxin, Eric D Bloch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Charge-Transfer Assembly of Electrically Conductive Metal-Organic Cages.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael R DworzakDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.
Christine M MontoneDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.ORCID http://orcid.org/0000-0002-1838-8002
Nicole I HalaszynskiDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, USA. cjk@udel.edu.ORCID http://orcid.org/0009-0002-5708-5722
Glenn P A YapDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.ORCID http://orcid.org/0000-0003-0385-387X
Christopher J KloxinDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, USA. cjk@udel.edu.ORCID http://orcid.org/0000-0002-1679-0022
Eric D BlochDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.ORCID http://orcid.org/0000-0003-4507-6247

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8M
High Sensitivity NMR Spectrometer with CryoprobeS10OD025185 · OD · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2019 to 2019
$930k
Macromolecular X-ray Crystallographic Data Collection SystemS10OD026896 · OD · UNIVERSITY OF DELAWARE · PI BAHNSON, BRIAN J · 2020 to 2020
$580k
High Performance Digital NMR SpectrometerS10RR026962 · NCRR · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2010 to 2010
$500k
NCRR NIH HHS S10 RR026962NIGMS NIH HHS P20 GM104316NIH HHS S10 OD025185NIH HHS S10 OD026896
6 · The paper itself

Abstract

Novel cobalt calixarene-capped and zirconium-based porous coordination cages were prepared with alkyne and azide functionality to leverage post-synthetic modification by click chemistry. While the calixarene-capped cages showed impressive stability when exposed to the most straightforward copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) reaction conditions with copper(II) sulfate and sodium ascorbate as the reducing agent, milder reaction conditions were necessary to perform analogous CuAAC reactions on zirconium-based cages. Reaction kinetics were monitored by IR spectroscopy, confirming rapid reaction times (<3 hours).

Identifiers

PMID37387311
PMCPMC11552439

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.