Evidence map›Paper›PMID 37386831›Full record

ArticleThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology2023

Circ-SNX27 sponging miR-375/RPN1 axis contributes to hepatocellular carcinoma progression.

Chao Zheng, Jin Liang, Shoude Yu, Hua Xu, Lin Dai, Dan Xu

Open access · diamondAbstract read
In one paragraph

Article in The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Circular RNA circAtxn10 regulates skeletal muscle cell differentiation by targeting miR-143-3p and Chrna1.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2025
    Article
  3. Article
  4. Article
  5. Translational cancer research · 2024
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chao ZhengSurgical Department, Wuhan Hospital of Traditional Chinese Medicine, Wuhan 430000, China.
Jin LiangDepartment of Spleen Stomach Disease and Hepatobiliary Disease, Wuhan Hospital of Traditional Chinese Medicine, Wuhan 430000, China.
Shoude YuDepartment of Spleen Stomach Disease and Hepatobiliary Disease, Wuhan Hospital of Traditional Chinese Medicine, Wuhan 430000, China.
Hua XuDepartment of Spleen Stomach Disease and Hepatobiliary Disease, Wuhan Hospital of Traditional Chinese Medicine, Wuhan 430000, China.
Lin DaiDepartment of Spleen Stomach Disease and Hepatobiliary Disease, Wuhan Hospital of Traditional Chinese Medicine, Wuhan 430000, China.
Dan XuDepartment of Spleen Stomach Disease and Hepatobiliary Disease, Wuhan Hospital of Traditional Chinese Medicine, Wuhan 430000, China.
Wuhan City Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is a prevalent malignant tumor with high fatality. It has yet to be reported whether circ-SNX27 can affect the progression of HCC. This study attempted to analyze circ-SNX27's precise role and underlying mechanisms in HCC. HCC cell lines and tumor specimens from HCC patients were analyzed using quantitative real-time PCR and Western blotting to quantify the expressions of circ-SNX27, miR-375, and ribophorin I (RPN1). Cell invasion and cell counting kit 8 experiments were conducted for the evaluation of HCC cell invasion and proliferation. Caspase-3 Activity Assay Kit was utilized to gauge the caspase-3 activity. Luciferase reporter and RNA immunoprecipitation assays were executed to ascertain the relationships among miR-375, circ-SNX27, and RPN1. To determine how circ-SNX27 knockdown affects the growth of HCC xenografts

Indexed as

circRNAHepatocellular carcinomamiRNAProliferationSponging activity

Identifiers

PMID37386831
PMCPMC10316188
OpenAlexW4382631659

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.