Evidence map›Paper›PMID 37386815›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Lactate Efflux Inhibition by Syrosingopine/LOD Co-Loaded Nanozyme for Synergetic Self-Replenishing Catalytic Cancer Therapy and Immune Microenvironment Remodeling.

Shengming Wu, Lehua Xu, Chenlong He, Peng Wang, Jingwen Qin, Fangfang Guo, Yilong Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  9. The moonlighting functions of glycolytic enzymes in tumorigenesis.Cellular oncology (Dordrecht, Netherlands) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shengming WuThe Institute for Translational Nanomedicine, Shanghai East Hospital, The Institute for Biomedical Engineering and Nano Science, School of Medicine, Tongji University, Shanghai, 200092, P. R. China.
Lehua XuThe Institute for Translational Nanomedicine, Shanghai East Hospital, The Institute for Biomedical Engineering and Nano Science, School of Medicine, Tongji University, Shanghai, 200092, P. R. China.
Chenlong HeThe Institute for Translational Nanomedicine, Shanghai East Hospital, The Institute for Biomedical Engineering and Nano Science, School of Medicine, Tongji University, Shanghai, 200092, P. R. China.
Peng WangThe Institute for Translational Nanomedicine, Shanghai East Hospital, The Institute for Biomedical Engineering and Nano Science, School of Medicine, Tongji University, Shanghai, 200092, P. R. China.
Jingwen QinThe Institute for Translational Nanomedicine, Shanghai East Hospital, The Institute for Biomedical Engineering and Nano Science, School of Medicine, Tongji University, Shanghai, 200092, P. R. China.
Fangfang GuoThe Institute for Translational Nanomedicine, Shanghai East Hospital, The Institute for Biomedical Engineering and Nano Science, School of Medicine, Tongji University, Shanghai, 200092, P. R. China.
Yilong WangThe Institute for Translational Nanomedicine, Shanghai East Hospital, The Institute for Biomedical Engineering and Nano Science, School of Medicine, Tongji University, Shanghai, 200092, P. R. China.ORCID 0000-0001-7483-9296

Funding

Ethics Board of Tongji University TJAA09722102Fundamental Research Funds for the Central UniversitiesNational Natural Science Foundation of China 32071395National Natural Science Foundation of China 32271439
6 · The paper itself

Abstract

An effective systemic mechanism regulates tumor development and progression; thus, a rational design in a one-stone-two-birds strategy is meant for cancer treatment. Herein, a hollow Fe

Indexed as

Lactic AcidNeoplasmsBiological TransportHumansMixed Function OxygenasesReserpineTumor Microenvironmentlactate 2-monooxygenaseLactic AcidMixed Function OxygenasesReserpinesyrosingopinelactate effluxnanocatalytic reactionsynergetic therapysyrosingopinetumor immunosuppressive microenvironment

Identifiers

PMID37386815
PMCPMC10502866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.