Evidence map›Paper›PMID 37386526›Full record

ArticlePorcine health management2023

Pathobiological analysis of african swine fever virus contact-exposed pigs and estimation of the basic reproduction number of the virus in Vietnam.

Sang-Ik Oh, Ngoc Anh Bui, Vuong Nghia Bui, Duy Tung Dao, Ara Cho, Han Gyu Lee, Young-Hun Jung, Yoon Jung Do, Eunju Kim, Eun-Yeong Bok and 2 more

Open access · goldAbstract read
In one paragraph

Article in Porcine health management, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Sang-Ik Oh *Division of Animal Diseases & Health, Rural Development Administration, National Institute of Animal Science, Wanju, 55365, Republic of Korea.
Ngoc Anh Bui *Virology Department, National Institute of Veterinary Research, Hanoi, Vietnam.
Vuong Nghia BuiVirology Department, National Institute of Veterinary Research, Hanoi, Vietnam.
Duy Tung DaoVirology Department, National Institute of Veterinary Research, Hanoi, Vietnam.
Ara ChoDivision of Animal Diseases & Health, Rural Development Administration, National Institute of Animal Science, Wanju, 55365, Republic of Korea.
Han Gyu LeeDivision of Animal Diseases & Health, Rural Development Administration, National Institute of Animal Science, Wanju, 55365, Republic of Korea.
Young-Hun JungDivision of Animal Diseases & Health, Rural Development Administration, National Institute of Animal Science, Wanju, 55365, Republic of Korea.
Yoon Jung DoDivision of Animal Diseases & Health, Rural Development Administration, National Institute of Animal Science, Wanju, 55365, Republic of Korea.
Eunju KimDivision of Animal Diseases & Health, Rural Development Administration, National Institute of Animal Science, Wanju, 55365, Republic of Korea.
Eun-Yeong BokDivision of Animal Diseases & Health, Rural Development Administration, National Institute of Animal Science, Wanju, 55365, Republic of Korea.
Tai-Young HurDivision of Animal Diseases & Health, Rural Development Administration, National Institute of Animal Science, Wanju, 55365, Republic of Korea.
Hu Suk LeeInternational Livestock Research Institute, Hanoi, Vietnam. h.s.lee@cgiar.org.
National Institute of Animal Science · KRRural Development Administration · KRNational Institute of Veterinary Research · VNJeonbuk National University · KR

Funding

Rural Development Administration PJ01651701
6 · The paper itself

Abstract

backgroundAfrican swine fever (ASF), caused by African swine fever virus (ASFV), is a fatal disease affecting wild and domestic pigs. Since China reported the first ASF outbreak in August 2018, ASFV has swept over the neighbouring Asian countries. However, studies involving experimental pig-to-pig ASFV transmission in Vietnam are lacking. The main objective of this experimental study was to demonstrate the pathobiological characteristics of ASFV contact-exposed pigs and estimate their basic reproduction number (R

resultsThe inoculated pig died 6 days post-inoculation, and the final survival rate was 90.0%. We started observing viremia and excretion of ASFV 10 days post-exposure in contact-exposed pigs. Unlike the surviving and negative control pigs, all necropsied pigs showed severe congestive splenomegaly and moderate-to-severe haemorrhagic lesions in the lymph nodes. The surviving pig presented with mild haemorrhagic lesions in the spleen and kidneys. We used Susceptible-Infectious-Removed models for estimating R

conclusionsThis study revealed pathobiological and epidemiological information in about pig-to-pig ASFV transmission. Our findings suggested that culling infected herds within a brief period of time may mitigate the spread of ASF outbreaks.

Indexed as

African swine feverAfrican swine fever virusBasic reproduction number (R0)PathobiologyTransmission rate (β)Vietnam

Identifiers

PMID37386526
PMCPMC10311738
OpenAlexW4382632007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.