Evidence map›Paper›PMID 37386430›Full record

SynthesisBMC public health2023

A systematic review of interventions to promote HPV vaccination globally.

Cam Escoffery, Courtney Petagna, Christine Agnone, Stephen Perez, Lindsay B Saber, Grace Ryan, Meena Dhir, Swathi Sekar, Katherine A Yeager, Caitlin B Biddell and 7 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 5 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 5 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
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  9. Article
  10. Article
  11. Article
  12. A Comparative Policy Analysis of HPV Vaccination Guidelines: Actors, Context, Content, and Process Across Eight Countries.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2026
    Article
  13. Article
  14. Article
  15. Co-creating HPV Vaccination Messages for Rural Washington: Application of a Boot Camp Translation Approach.Health education & behavior : the official publication of the Society for Public Health Education · 2026
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Primary Care Providers' Perspectives on Barriers and Facilitators to Human Papillomavirus (HPV) Vaccination among Young Adults: A Qualitative Study.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

Cam EscofferyRollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA, 30322, 404-727-4701, USA. cescoff@emory.edu.
Courtney PetagnaRollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA, 30322, 404-727-4701, USA.
Christine AgnoneRollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA, 30322, 404-727-4701, USA.
Stephen PerezRollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA, 30322, 404-727-4701, USA.
Lindsay B SaberRollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA, 30322, 404-727-4701, USA.
Grace RyanDepartment of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Meena DhirRollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA, 30322, 404-727-4701, USA.
Swathi SekarRollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA, 30322, 404-727-4701, USA.
Katherine A YeagerNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
Caitlin B BiddellGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, Durham, NC, USA.
Purnima MadhivananMel & Enid Zuckerman College of Public Health, University of Arizona, Tucson, USA.
Stephanie LeeNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
Amanda S EnglishInstitute for Health Disparities, University of North Texas Health Science Center, Fort Worth, TX, USA.
Lara SavasCenter for Health Promotion and Prevention Research, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Eliza DalyPrevention Research Center, College of Public Health, University of Iowa, Iowa City, IA, USA.
Thuy VuHealth Promotion Research Center, School of Public Health, University of Washington, Seattle, WA, USA.
Maria E FernandezCenter for Health Promotion and Prevention Research, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
Emory University · USThe University of Texas Health Science Center at Houston · USUniversity of Arizona · USUniversity of Iowa · USUniversity of Massachusetts Chan Medical School · USUniversity of North Carolina at Chapel Hill · USUniversity of North Texas Health Science Center · USUniversity of Washington · US

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
University of Texas Prevention Research CenterU48DP006408 · DP · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FERNANDEZ, MARIA EULALIA, MARKHAM, CHRISTINE MARGARET · 2018 to 2023
$3.5M
Cancer Care Quality Training ProgramT32CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ETHAN M. BASCH, Stephanie Brooke Wheeler · 2018 to 2026
$3.0M
Prevention And Control of Cancer: Training for Change in Individuals and SystemsT32CA172009 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEMON, STEPHENIE C., OCKENE, JUDITH K · 2019 to 2023
$1.5M
CDC HHS U48DP006377CDC HHS U48DP006389CDC HHS U48DP006398CDC HHS U48DP006400CDC HHS U48DP006413NCCDPHP CDC HHS U48 DP006377NCCDPHP CDC HHS U48 DP006389NCCDPHP CDC HHS U48 DP006398NCCDPHP CDC HHS U48 DP006400NCCDPHP CDC HHS U48 DP006408NCCDPHP CDC HHS U48 DP006413NCI NIH HHS P30 CA023074NCI NIH HHS T32 CA116339NCI NIH HHS T32 CA172009NIH HHS P30CA023074-41NIH HHS T32-CA-116339NIH HHS T32-CA-172009
6 · The paper itself

Abstract

backgroundDespite the human papillomavirus (HPV) vaccine being a safe, effective cancer prevention method, its uptake is suboptimal in the United States (U.S.). Previous research has found a variety of intervention strategies (environmental and behavioral) to increase its uptake. The purpose of the study is to systematically review the literature on interventions that promote HPV vaccination from 2015 to 2020.

methodsWe updated a systematic review of interventions to promote HPV vaccine uptake globally. We ran keyword searches in six bibliographic databases. Target audience, design, level of intervention, components and outcomes were abstracted from the full-text articles in Excel databases.

resultsOf the 79 articles, most were conducted in the U.S. (72.2%) and in clinical (40.5%) or school settings (32.9%), and were directed at a single level (76.3%) of the socio-ecological model. Related to the intervention type, most were informational (n = 25, 31.6%) or patient-targeted decision support (n = 23, 29.1%). About 24% were multi-level interventions, with 16 (88.9%) combining two levels. Twenty-seven (33.8%) reported using theory in intervention development. Of those reporting HPV vaccine outcomes, post-intervention vaccine initiation ranged from 5% to 99.2%, while series completion ranged from 6.8% to 93.0%. Facilitators to implementation were the use of patient navigators and user-friendly resources, while barriers included costs, time to implement and difficulties of integrating interventions into the organizational workflow.

conclusionsThere is a strong need to expand the implementation of HPV-vaccine promotion interventions beyond education alone and at a single level of intervention. Development and evaluation of effective strategies and multi-level interventions may increase the uptake of the HPV vaccine among adolescents and young adults.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesAdolescentCognitionHumansImmunizationVaccinationYoung AdultPapillomavirus VaccinesAdolescentHealth promotionHPV vaccinationInterventionsVaccinationYoung adults

Identifiers

PMID37386430
PMCPMC10308645
OpenAlexW4382631050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.