Carboligation of 5-(hydroxymethyl)furfural via whole-cell catalysis to form C12 furan derivatives and their use for hydrazone formation.

Sara Jonsdottir Glaser, Sang-Hyun Pyo, Nicola Rehnberg, Dörte Rother, Rajni Hatti-Kaul

Abstract read

In one paragraph

Article in Microbial cell factories, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sara Jonsdottir GlaserDivision of Biotechnology, Department of Chemistry, Center for Chemistry and Chemical Engineering, Lund University, 22100, Lund, Sweden.ORCID http://orcid.org/0000-0002-8430-1075

Sang-Hyun PyoDivision of Biotechnology, Department of Chemistry, Center for Chemistry and Chemical Engineering, Lund University, 22100, Lund, Sweden.ORCID http://orcid.org/0000-0002-5037-2748

Nicola RehnbergCentre for Analysis and Synthesis, Department of Chemistry, Lund University, Box 124, SE-22100, Lund, Sweden.ORCID http://orcid.org/0000-0002-1326-5054

Dörte RotherBona Sweden AB, Box 210 74, SE-200 21, Malmö, Sweden.ORCID http://orcid.org/0000-0002-2339-4431

Rajni Hatti-KaulDivision of Biotechnology, Department of Chemistry, Center for Chemistry and Chemical Engineering, Lund University, 22100, Lund, Sweden. rajni.hatti-kaul@biotek.lu.se.ORCID http://orcid.org/0000-0001-5229-5814

Funding

Svenska Forskningsrådet Formas 942-2016-33

6 · The paper itself

Abstract

backgroundBiobased 5-(hydroxymethyl)furfural (5-HMF) is an important platform that offers numerous possibilities for upgrading to a range of chemical, material and fuel products. One reaction of special interest is the carboligation of 5-HMF into C

objectivesThis study was aimed at evaluating the use of whole cells of Escherichia coli carrying recombinant Pseudomonas fluorescens benzaldehyde lyase as biocatalysts for 5-HMF carboligation, recovery of the C

resultsThe reaction with 5 g/L 5-HMF using 2 g

conclusionThe study demonstrates the potential application of recombinant E. coli cells for cost-effective production of commercially relevant products.

Indexed as

Escherichia coliFuransCatalysisFuraldehydeHydrazones5-hydroxymethylfurfuralFuraldehydeFuransHydrazones5,5’-bis(hydroxymethyl)furil (BHMF)5,5’-bis(hydroxymethyl)furoin (DHMF)5-(hydroxymethyl)furfuralBenzaldehyde lyaseHydrazoneWhole-cell biocatalyst

Identifiers

PMID37386409

DOI10.1186/s12934-023-02130-1

PMCPMC10311727

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.