Evidence map›Paper›PMID 37386332›Full record

ReviewLangenbeck's archives of surgery2023

Minimally invasive versus open adrenalectomy for adrenocortical carcinoma: the keys surgical factors influencing the outcomes-a collective overview.

Alessio Giordano, Francesco Feroci, Mauro Podda, Emanuele Botteri, Monica Ortenzi, Giulia Montori, Mario Guerrieri, Nereo Vettoretto, Ferdinando Agresta, Carlo Bergamini

Abstract readReview
PubMed Publisher
In one paragraph

Review in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Contemporary Approaches to Adrenocortical Carcinoma.Hematology/oncology clinics of North America · 2026
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessio GiordanoDepartment of Surgery, General Surgery unit, S. Stefano Hospital, Azienda ASL Toscana Centro, Suor Niccolina Infermiera 20/22, 59100, Prato, Italy. alessio.giordano8@gmail.com.ORCID https://orcid.org/0000-0002-9505-791X
Francesco FerociDepartment of Surgery, General Surgery unit, S. Stefano Hospital, Azienda ASL Toscana Centro, Suor Niccolina Infermiera 20/22, 59100, Prato, Italy.
Mauro PoddaDepartment of Surgery, General Surgery Unit, University Hospital of Cagliari, Cagliari, Italy.
Emanuele BotteriGeneral Surgery Unit, ASST Spedali Civili Di Brescia, Montichiari, Italy.
Monica OrtenziDepartment of General Surgery, Università Politecnica Delle Marche, Ancona, Italy.
Giulia MontoriDepartment of General Surgery, Ulss2 Marca Trevigiana, Vittorio Veneto, Italy.
Mario GuerrieriDepartment of General Surgery, Università Politecnica Delle Marche, Ancona, Italy.
Nereo VettorettoGeneral Surgery Unit, ASST Spedali Civili Di Brescia, Montichiari, Italy.
Ferdinando AgrestaDepartment of General Surgery, Ulss2 Marca Trevigiana, Vittorio Veneto, Italy.
Carlo BergaminiDepartment of Emergency, Emergency General Surgery Unit, AOU Careggi, Firenze, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAdrenocortical carcinoma (A.C.C.) is a rare tumour, often discovered at an advanced stage and associated with a poor prognosis. Surgery is the treatment of choice. We aimed to review the different surgical approaches trying to compare their outcome.

methodsThis comprehensive review has been carried out according to the PRISMA statement. The literature search was performed in PubMed, Scopus, the Cochrane Library and Google Scholar.

resultsAmong all studies identified, 18 were selected for the review. A total of 14,600 patients were included in the studies, of whom 4421 were treated by mini-invasive surgery (M.I.S.). Ten studies reported 531 conversions from M.I.S. to an open approach (OA) (12%). Differences were reported for operative times as well as for postoperative complications more often in favour of OA, whereas differences for hospitalization time in favour of M.I.S. Some studies showed an R0 resection rate from 77 to 89% for A.C.C. treated by OA and 67 to 85% for tumours treated by M.I.S. The overall recurrence rate ranged from 24 to 29% for A.C.C. treated by OA and from 26 to 36% for tumours treated by M.I.S.

conclusionsOA should still be considered the standard surgical management of A.C.C. Laparoscopic adrenalectomy has shown shorter hospital stays and faster recovery compared to open surgery. However, the laparoscopic approach resulted in the worst recurrence rate, time to recurrence and cancer-specific mortality in stages I-III ACC. The robotic approach had similar complications rate and hospital stays, but there are still scarce results about oncologic follow-up.

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical CarcinomaAdrenalectomyHospitalizationHumansLength of StayAdrenalcortical carcinomaLaparoscopic adrenalectomyMininvasive surgeryOpen adrenalectomyRobotic adrenalectomy

Identifiers

PMID37386332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.