ArticleEuropean journal of pediatrics2023
Platelet indices in overweight and obese children.
Article in European journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Association of Leukocyte, Erythrocyte, and Platelet Counts with Metabolic Syndrome and Its Components in Young Individuals without Overt Signs of Inflammation: A Cross-Sectional Study.Children (Basel, Switzerland) · 2024Article
- Predictive markers of metabolically healthy obesity in children and adolescents: can AST/ALT ratio serve as a simple and reliable diagnostic indicator?European journal of pediatrics · 2024Article
- Plasminogen Activator Inhibitor-1 and Vitamin D Association in the Overweight and Obese Pediatric Population.Nutrients · 2023Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to determine the association between platelet indices and obesity in children. A total of 190 overweight or obese children (mean age: 13.29 ± 2.54, M/F: 0.74) and 100 normal-weight children (mean age: 12.72 ± 2.23, M/F:1.04) were enrolled in the study. Platelet count (PLT), platelet indices, and ratios were determined. No significant difference was observed in terms of mean platelet volume (MPV) and platelet distribution width (PDW) levels and MPV/plateletcrit (PCT) and PDW/PCT ratios between overweight, obese, and normal-weight groups, whereas significant differences were observed in terms of PLT, PCT, MPV/PLT, and PDW/PLT ratios between each group. PLT and PCT levels were significantly higher in the obese group than in the overweight and normal-weight groups (P = 0.003, P = 0.002, respectively). Children with obesity had lower MPV/PLT and PDW/PLT ratios than the other groups (P = 0.001, P = 0.02, respectively). Overweight and obese children with insulin resistance (IR) had higher PLT and lower MPV/PLT, and PDW/PLT ratios than the children without IR (P = 0.034, P = 0.04, P = 0.013, respectively).
conclusionSignificant differences were observed in terms of PLT, PCT, MPV/PLT, and PDW/PLT between overweight, obese, and normal-weight children. WHAT IS KNOWN: • Obesity is associated with a chronic low-grade systemic inflammation. • Platelets play a crucial role in coagulation, hemostasis, thrombosis, immunomodulatory processes, inflammation, and atherothrombosis. WHAT IS NEW: • Significant differences were observed in terms of PLT, PCT, MPV/PLT, and PDW/PLT between overweight, obese, and normal-weight children. • Overweight and obese children with insulin resistance had higher PLT and lower MPV/PLT and PDW/PLT ratios than the children without insülin resistance.
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