ArticleNature plants2023
SIAMESE-RELATED1 imposes differentiation of stomatal lineage ground cells into pavement cells.
Article in Nature plants, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- HOMEODOMAIN-LIKE shapes chromatin architecture and rewires leaf epidermal patterns.Nature communications · 2026Article
- Stomatal XVE: an inducible system for cell-stage-specific gene expression and editing in the stomatal lineage.The New phytologist · 2026Article
- Cell cycle in plant development and reprogramming.Development (Cambridge, England) · 2026Review
- Cytoskeletal control of development and environmental adaptation in plants.Science China. Life sciences · 2026Review
- A common pathway controls cell size in the sepal and leaf epidermis leading to a nonrandom pattern of giant cells.PLoS biology · 2025Article
- Warm temperature modifies cell fates to reduce stomata production in Arabidopsis.The New phytologist · 2025Article
- Leaf form diversity and evolution: a never-ending story in plant biology.Journal of plant research · 2024Review
- The SIAMESE family of cell-cycle inhibitors in the response of plants to environmental stresses.Frontiers in plant science · 2024Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
The leaf epidermis represents a multifunctional tissue consisting of trichomes, pavement cells and stomata, the specialized cellular pores of the leaf. Pavement cells and stomata both originate from regulated divisions of stomatal lineage ground cells (SLGCs), but whereas the ontogeny of the stomata is well characterized, the genetic pathways activating pavement cell differentiation remain relatively unexplored. Here, we reveal that the cell cycle inhibitor SIAMESE-RELATED1 (SMR1) is essential for timely differentiation of SLGCs into pavement cells by terminating SLGC self-renewal potency, which depends on CYCLIN A proteins and CYCLIN-DEPENDENT KINASE B1. By controlling SLGC-to-pavement cell differentiation, SMR1 determines the ratio of pavement cells to stomata and adjusts epidermal development to suit environmental conditions. We therefore propose SMR1 as an attractive target for engineering climate-resilient plants.
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Registered trials
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