ArticleScientific reports2023
Isolation and genomic characterization of one novel goose astrovirus causing acute gosling gout in China.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Impact of GAstV-2 infection on intestinal microbiota and renal gene transcriptome in goslings.Poultry science · 2026Article
- Genomic characterization, recombination analysis and pathogenicity of goose astrovirus 2 isolated from geese in Jiangxi Province, China.Poultry science · 2026Article
- Identification and genomic characterization of a goose astrovirus in Henan Province, China.Frontiers in veterinary science · 2026Article
- Rapid extraction-free RT-RAA assay for on-site detection of goose astrovirus type 1 in goslings.Frontiers in cellular and infection microbiology · 2026Article
- Whole-genome characterization and evolutionary analysis of a novel duck reovirus isolated fromVeterinary world · 2025Article
- Review
- High-Throughput Sequencings Revealed That Gut Microbiota Dysbiosis is Implicated in Gouty Arthritis of Red-Crowned Crane (Transboundary and emerging diseases · 2025Article
- Cinnamomi cortex extract mitigated monosodium urate-induced acute gouty arthritis in rats through nuclear factor-κB-NOD-like receptor thermal protein domain associated protein 3 signaling pathway.The Journal of veterinary medical science · 2024Article
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Authors and funding
8 authors.
Funding
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Abstract
Novel goose astrovirus (NGAstV) is a member of the genus Avain Avastrovirus (AAstV) and the family Astroviridae. NGAstV-associated gout disease has caused huge economic losses to the goose industry worldwide. Since early 2020, NGAstV infections characterized by articular and visceral gout emerged continuously in China. Herein, we isolated a GAstV strain from goslings with fatal gout disease and sequenced its complete genome nucleotide sequence. Then we conducted systematic genetic diversity and evolutionary analysis. The results demonstrated that two genotypic species of GAstV (GAstV-I and GAstV-II) were circulating in China, and GAstV-II sub-genotype IId had become the dominant one. Multiple alignments of amino acid sequences of GAstV capsid protein revealed that several characteristic mutations (E456D, A464N, and L540Q) in GAstV-II d strains, as well as additional residues in the newly identified isolate which varied over time. These findings enrich the understanding of the genetic diversity and evolution of GAstV and may facilitate the development of effective preventive strategies.
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