Evidence map›Paper›PMID 37385734›Full record

Observational studyBMJ paediatrics open2023

Parental detection of neonatal jaundice using a low-cost colour card: a multicentre prospective study.

Guochang Xue, Huali Zhang, Xuexing Ding, Fu Xiong, Yanhong Liu, Hui Peng, Changlin Wang, Yi Zhao, Huili Yan, Mingxing Ren and 24 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in BMJ paediatrics open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Guochang XueDepartment of Paediatrics, Wuxi Ninth People's Hospital affiliated to Soochow University, Wuxi, Jiangsu, China gcxue@163.com.ORCID 0000-0002-7890-8575
Huali ZhangDepartment of Paediatrics, The People's Hospital of Zhenping, Zhenping, Henan, China.
Xuexing DingDepartment of Paediatrics, The People's Hospital of Anyang, Anyang, Henan, China.
Fu XiongDepartment of Paediatrics, Sichuan Provincial Hospital for Women and Children, Chengdu, Sichuan, China.
Yanhong LiuDepartment of Neonatal, The People's Hospital of Zhengzhou, Zhengzhou, Henan, China.
Hui PengDepartment of Paediatrics, The Third People's Hospital of Jingzhou, Jingzhou, Hubei, China.
Changlin WangDepartment of Neonatal, Affiliated Children's Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Yi ZhaoDepartment of Neonatal, Kaifeng Maternal and Child Health Hospital, Kaifeng, Henan, China.
Huili YanDepartment of Neonatal, Jiaozuo Maternal and Child Health Hospital, Jiaozuo, Henan, China.
Mingxing RenDepartment of Paediatrics, Wuxi Ninth People's Hospital affiliated to Soochow University, Wuxi, Jiangsu, China.
Chaoying MaDepartment of Paediatrics, Wuxi Ninth People's Hospital affiliated to Soochow University, Wuxi, Jiangsu, China.
Hanming LuDepartment of Paediatrics, Wuxi Ninth People's Hospital affiliated to Soochow University, Wuxi, Jiangsu, China.
Yanli LiDepartment of Paediatrics, The People's Hospital of Zhenping, Zhenping, Henan, China.
Ruifeng MengDepartment of Paediatrics, The People's Hospital of Zhenping, Zhenping, Henan, China.
Lingjun XieDepartment of Paediatrics, The People's Hospital of Zhenping, Zhenping, Henan, China.
Na ChenDepartment of Paediatrics, The People's Hospital of Anyang, Anyang, Henan, China.
Xiufang ChengDepartment of Paediatrics, The People's Hospital of Anyang, Anyang, Henan, China.
Jiaojiao WangDepartment of Paediatrics, The People's Hospital of Anyang, Anyang, Henan, China.
Xiaohong XinDepartment of Paediatrics, The People's Hospital of Anyang, Anyang, Henan, China.
Ruifen WangDepartment of Paediatrics, The People's Hospital of Anyang, Anyang, Henan, China.
Qi JiangDepartment of Paediatrics, Sichuan Provincial Hospital for Women and Children, Chengdu, Sichuan, China.
Yong ZhangDepartment of Paediatrics, Sichuan Provincial Hospital for Women and Children, Chengdu, Sichuan, China.
Guijuan LiangDepartment of Neonatal, The People's Hospital of Zhengzhou, Zhengzhou, Henan, China.
Yuanzheng LiDepartment of Neonatal, The People's Hospital of Zhengzhou, Zhengzhou, Henan, China.
Jianing KangDepartment of Neonatal, The People's Hospital of Zhengzhou, Zhengzhou, Henan, China.
Huimin ZhangDepartment of Neonatal, The People's Hospital of Zhengzhou, Zhengzhou, Henan, China.
Yinying ZhangDepartment of Paediatrics, The Third People's Hospital of Jingzhou, Jingzhou, Hubei, China.
Yuan YuanDepartment of Paediatrics, The Third People's Hospital of Jingzhou, Jingzhou, Hubei, China.
Yawen LiDepartment of Neonatal, Affiliated Children's Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Yinglin SuDepartment of Neonatal, Affiliated Children's Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Junping LiuDepartment of Neonatal, Kaifeng Maternal and Child Health Hospital, Kaifeng, Henan, China.
Shengjie DuanDepartment of Neonatal, Kaifeng Maternal and Child Health Hospital, Kaifeng, Henan, China.
Qingsheng LiuDepartment of Neonatal, Jiaozuo Maternal and Child Health Hospital, Jiaozuo, Henan, China.
Jing WeiDepartment of Neonatal, Jiaozuo Maternal and Child Health Hospital, Jiaozuo, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince most infants are usually discharged before age 48-72 hours, peak bilirubin levels will almost always occur after discharge. Parents may be the first to observe the onset of jaundice after discharge, but visual assessment is unreliable. The jaundice colour card (JCard) is a low-cost icterometer designed for the assessment of neonatal jaundice. The objective of this study was to evaluate parental use of JCard to detect jaundice in neonates.

methodsWe conducted a multicentre, prospective, observational cohort study in nine sites across China. A total of 1161 newborns ≥35 weeks of gestation were enrolled in the study. Measurements of total serum bilirubin (TSB) levels were based on clinical indications. The JCard measurements by parents and paediatricians were compared with the TSB.

resultsJCard values of parents and paediatricians were correlated with TSB (r=0.754 and 0.788, respectively). The parents' and paediatricians' JCard values 9 had sensitivities of 95.2% vs 97.6% and specificities of 84.5% vs 71.7% for identifying neonates with TSB ≥153.9 µmol/L. The parents' and paediatricians' JCard values 15 had sensitivities of 79.9% vs 89.0% and specificities of 66.7% vs 64.9% for identifying neonates with TSB ≥256.5 µmol/L. Areas under the receiver operating characteristic curves of parents for identifying TSB ≥119.7, ≥153.9, ≥205.2, and ≥256.5 µmol/L were 0.967, 0.960, 0.915, and 0.813, respectively, and those of paediatricians were 0.966, 0.961, 0.926 and 0.840, respectively. The intraclass correlation coefficient was 0.933 between parents and paediatricians.

conclusionThe JCard can be used to classify different levels of bilirubin, but it is less accurate with high bilirubin levels. The JCard diagnostic performance of parents was slightly lower than that of paediatricians.

Indexed as

Jaundice, NeonatalAgedBilirubinHumansInfantInfant, NewbornMiddle AgedParentsProspective StudiesBilirubinJaundiceNeonatology

Identifiers

PMID37385734
PMCPMC10314627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.