Evidence map›Paper›PMID 37385677›Full record

ArticleAJNR. American journal of neuroradiology2023

Long-Term Imaging Follow-up from the Management of Myelomeningocele Study.

E George, C MacPherson, S Pruthi, L Bilaniuk, J Fletcher, A Houtrow, N Gupta, O A Glenn

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Outcomes in prenatal vs. postnatal surgery for myelomeningocele: a systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Pooled it
  2. Article
  3. Differences in brain development and need for CSF diversion based on MMC level: Comparison between prenatal and postnatal repair.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  4. Article
  5. Article
  6. Regression of Chiari malformation type 2 following early postnatal meningomyelocele repair-a retrospective observation from an institutional series of patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  7. Intracranial volumetric evaluation in postnatally repaired myelomeningocele infants.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  8. A qualitative analysis of patient and caregiver experiences with myelomeningocele through online discussion boards.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

E GeorgeFrom the Departments of Radiology and Biomedical Imaging (E.G., O.A.G.).ORCID 0000-0003-3141-5738
C MacPhersonBiostatistics Center (C.M.), Milken Institute School of Public Health, The George Washington University, Washington, DC.ORCID 0009-0002-8868-4912
S PruthiDepartment of Radiology (S.P.), Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee.ORCID 0000-0002-4035-0852
L BilaniukDepartment of Radiology (L.B.), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.ORCID 0000-0002-3817-1142
J FletcherDepartment of Psychology (J.F.), University of Houston, Houston, Texas.ORCID 0000-0002-1181-6721
A HoutrowDepartment of Physical Medicine and Rehabilitation (A.H.), University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0003-2906-8896
N GuptaNeurological Surgery (N.G.).ORCID 0000-0001-9539-7052
O A GlennFrom the Departments of Radiology and Biomedical Imaging (E.G., O.A.G.) Orit.Glenn@ucsf.edu.ORCID 0000-0002-4642-1252
Laboratoire d’Imagerie Biomédicale · FRChildren's Hospital of Philadelphia · USMilken Institute · USMonroe Carell Jr. Children's Hospital · USUniversity of California, San Francisco · USUniversity of Houston · USUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeShort-term results demonstrate that prenatal repair of a myelomeningocele is associated with a reduction in hydrocephalus and an increased likelihood of the reversal of Chiari II malformations compared with postnatal repair. The purpose of this study was to identify the long-term imaging findings at school age among subjects who underwent pre- versus postnatal repair of a myelomeningocele. MATERIALS AND

methodsA subset of subjects enrolled in the Management of Myelomeningocele Study who underwent either prenatal (

resultsPrenatal repair of a myelomeningocele was associated with higher rates of normal location of fourth ventricle and lower rates of hindbrain herniation, cerebellar herniation, tectal beaking, brainstem distortion, and kinking at school age compared with postnatal repair (all

conclusionsPrenatal repair of a myelomeningocele is associated with persistent improvement in posterior fossa imaging findings of Chiari II malformation at school age compared with postnatal repair.

Indexed as

Arnold-Chiari MalformationHydrocephalusMeningomyeloceleBrainFemaleFollow-Up StudiesHumansPregnancy

Identifiers

PMID37385677
PMCPMC10337608
OpenAlexW4382536896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.