Evidence map›Paper›PMID 37385345›Full record

SynthesisJournal of sport and health science2024

The influence of resistance exercise training prescription variables on skeletal muscle mass, strength, and physical function in healthy adults: An umbrella review.

Jonathan C Mcleod, Brad S Currier, Caroline V Lowisz, Stuart M Phillips

Registry-linked trialOpen access · diamondAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of sport and health science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07484646 (Effects of Electrical Muscle Stimulation Combined With Resistance Training on Muscle Mass, Strength, Body Composition, and Power in Weight Lifters), which is not on this map. Cited by 88 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 12 pooled it
32.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07484646 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Electrical Muscle Stimulation Combined With Resistance Training on Muscle Mass, Strength, Body Composition, and Power in Weight Lifters

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2026Enrolled34ConditionsBody Composition, Muscle Mass, Muscle StrengthArmsEMS + Resistance Training, Resistance Training Only
3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 12 syntheses or guidelines pooled it, 133 citations in OpenAlex.

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  9. Effects of resistance training on breast cancer-related arm lymphedema: a systematic review and dose-response meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jonathan C McleodDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton L8S4L8, Canada.
Brad S CurrierDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton L8S4L8, Canada.
Caroline V LowiszDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton L8S4L8, Canada.
Stuart M PhillipsDepartment of Kinesiology, Faculty of Science, McMaster University, Hamilton L8S4L8, Canada. Electronic address: phillis@mcmaster.ca.
McMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this umbrella review was to determine the impact of resistance training (RT) and individual RT prescription variables on muscle mass, strength, and physical function in healthy adults.

methodsFollowing Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we systematically searched and screened eligible systematic reviews reporting the effects of differing RT prescription variables on muscle mass (or its proxies), strength, and/or physical function in healthy adults aged >18 years.

resultsWe identified 44 systematic reviews that met our inclusion criteria. The methodological quality of these reviews was assessed using A Measurement Tool to Assess Systematic Reviews; standardized effectiveness statements were generated. We found that RT was consistently a potent stimulus for increasing skeletal muscle mass (4/4 reviews provide some or sufficient evidence), strength (4/6 reviews provided some or sufficient evidence), and physical function (1/1 review provided some evidence). RT load (6/8 reviews provided some or sufficient evidence), weekly frequency (2/4 reviews provided some or sufficient evidence), volume (3/7 reviews provided some or sufficient evidence), and exercise order (1/1 review provided some evidence) impacted RT-induced increases in muscular strength. We discovered that 2/3 reviews provided some or sufficient evidence that RT volume and contraction velocity influenced skeletal muscle mass, while 4/7 reviews provided insufficient evidence in favor of RT load impacting skeletal muscle mass. There was insufficient evidence to conclude that time of day, periodization, inter-set rest, set configuration, set end point, contraction velocity/time under tension, or exercise order (only pertaining to hypertrophy) influenced skeletal muscle adaptations. A paucity of data limited insights into the impact of RT prescription variables on physical function.

conclusionOverall, RT increased muscle mass, strength, and physical function compared to no exercise. RT intensity (load) and weekly frequency impacted RT-induced increases in muscular strength but not muscle hypertrophy. RT volume (number of sets) influenced muscular strength and hypertrophy.

Indexed as

Resistance TrainingAdultExerciseExercise TherapyHumansHypertrophyMuscle, SkeletalHypertrophyResistance trainingResistance training prescription variablesStrengthUmbrella review

Identifiers

PMID37385345
PMCPMC10818109
OpenAlexW4382583037

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.