Evidence map›Paper›PMID 37385252›Full record

ArticleCell reports. Medicine2023

Fatal neonatal listeriosis following L. monocytogenes horizontal transmission highlights neonatal susceptibility to orally acquired listeriosis.

Caroline Charlier, Coralie Noel, Lukas Hafner, Alexandra Moura, Claire Mathiaud, Aurélia Pitsch, Chakib Meziane, Lydie Jolly-Sanchez, Astrid de Pontfarcy, Sylvain Diamantis and 8 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports. Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Comparative inactivation ofFrontiers in microbiology · 2026
    Article
  2. Listeriosis.Nature reviews. Disease primers · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Caroline CharlierInstitut Pasteur, Université Paris Cité, INSERM U1117, Biology of Infection Unit, 75015 Paris, France; Institut Pasteur, National Reference Center and WHO Collaborating Center Listeria, 75015 Paris, France; Cochin University Hospital, Division of Infectious Diseases and Tropical Medicine, APHP, Institut Imagine, 75015 Paris, France. Electronic address: caroline.charlier@pasteur.fr.
Coralie NoelGroupe Hospitalier Sud Ile-de-France, 77000 Melun, France.
Lukas HafnerInstitut Pasteur, Université Paris Cité, INSERM U1117, Biology of Infection Unit, 75015 Paris, France.
Alexandra MouraInstitut Pasteur, Université Paris Cité, INSERM U1117, Biology of Infection Unit, 75015 Paris, France; Institut Pasteur, National Reference Center and WHO Collaborating Center Listeria, 75015 Paris, France.
Claire MathiaudGroupe Hospitalier Sud Ile-de-France, 77000 Melun, France.
Aurélia PitschGroupe Hospitalier Sud Ile-de-France, 77000 Melun, France.
Chakib MezianeGroupe Hospitalier Sud Ile-de-France, 77000 Melun, France.
Lydie Jolly-SanchezGroupe Hospitalier Sud Ile-de-France, 77000 Melun, France.
Astrid de PontfarcyGroupe Hospitalier Sud Ile-de-France, 77000 Melun, France.
Sylvain DiamantisGroupe Hospitalier Sud Ile-de-France, 77000 Melun, France.
Hélène Bracq-DieyeInstitut Pasteur, National Reference Center and WHO Collaborating Center Listeria, 75015 Paris, France.
Olivier DissonInstitut Pasteur, Université Paris Cité, INSERM U1117, Biology of Infection Unit, 75015 Paris, France.
Pierre ThouvenotInstitut Pasteur, National Reference Center and WHO Collaborating Center Listeria, 75015 Paris, France.
Guillaume ValèsInstitut Pasteur, National Reference Center and WHO Collaborating Center Listeria, 75015 Paris, France.
Nathalie Tessaud-RitaInstitut Pasteur, National Reference Center and WHO Collaborating Center Listeria, 75015 Paris, France.
Mathieu TourdjmanSanté publique France, 94410 Saint Maurice, France.
Alexandre LeclercqInstitut Pasteur, National Reference Center and WHO Collaborating Center Listeria, 75015 Paris, France.
Marc LecuitInstitut Pasteur, Université Paris Cité, INSERM U1117, Biology of Infection Unit, 75015 Paris, France; Institut Pasteur, National Reference Center and WHO Collaborating Center Listeria, 75015 Paris, France; Necker-Enfants Malades University Hospital, Division of Infectious Diseases and Tropical Medicine, APHP, Institut Imagine, 75015 Paris, France. Electronic address: marc.lecuit@pasteur.fr.
Melun Hospital · FRInserm · FRInstitut Pasteur · FRSanté Publique France · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of fulminant fatal neonatal listeriosis due to horizontal transmission of Listeria monocytogenes (Lm) in a neonatal double room. Genomic analyses reveal a close genetic relationship between clinical isolates, supporting cross-contamination. Oral inoculation experiments in adult and neonatal mice show that neonates are susceptible to a low Lm inoculum and that this susceptibility results from the immaturity of the neonatal gut microbiota. Infected neonates should therefore be isolated for as long as they shed Lm in their feces to avoid horizontal transmission and its dire consequences.

Indexed as

Infant, Newborn, DiseasesListeria monocytogenesListeriosisAnimalsDisease Transmission, InfectiousHumansInfant, NewbornMicecross-contaminationhorizontal transmissioninfectionListeria monocytogeneslisteriosismeningitismicrobiotanewbornnosocomialuniversal precaution

Identifiers

PMID37385252
PMCPMC10394164
OpenAlexW4382393760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.