ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2023
Frequency-swept dynamic nuclear polarization.
Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- High-frequency dynamic nuclear polarization in rotating solids.Science advances · 2026Review
- Imaging cell phone radiation in tissue mimics with hyperpolarized low-field MRI.Science advances · 2026Article
- Effective Hamiltonian-Based DNP Sequence Optimization.The journal of physical chemistry letters · 2026Article
- Proton hyperfine couplings and Overhauser DNP.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2024Article
- Dipolar Recoupling in Rotating Solids.Chemical reviews · 2024Review
- Dynamic Nuclear Polarization with P1 Centers in Diamond.The journal of physical chemistry letters · 2024Article
- Frequency-Chirped Magic Angle Spinning Dynamic Nuclear Polarization Combined with Electron Decoupling.The journal of physical chemistry letters · 2024Article
- Design and optimization of THz coupling in zirconia MAS rotors for dynamic nuclear polarization NMR.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2024Article
- Resonant Mixing Dynamic Nuclear Polarization.The journal of physical chemistry letters · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Dynamic nuclear polarization (DNP) improves the sensitivity of NMR spectroscopy by the transfer of electron polarization to nuclei via irradiation of electron-nuclear transitions with microwaves at the appropriate frequency. For fields > 5 T and using g ∼ 2 electrons as polarizing agents, this requires the availability of microwave sources operating at >140 GHz. Therefore, microwave sources for DNP have generally been continuous-wave (CW) gyrotrons, and more recently solid state, oscillators operating at a fixed frequency and power. This constraint has limited the DNP mechanisms which can be exploited, and stymied the development of new time domain mechanisms. We report here the incorporation of a microwave source enabling facile modulation of frequency, amplitude, and phase at 9 T (250 GHz microwave frequency), and we have used the source for magic-angle spinning (MAS) NMR experiments. The experiments include investigations of CW DNP mechanisms, the advantage of frequency-chirped irradiation, and a demonstration of an Overhauser enhancement of ∼25 with a recently reported water-soluble BDPA radical, highlighting the potential for affordable and compact microwave sources to achieve significant enhancement in aqueous samples, including biological macromolecules. With the development of suitable microwave amplifiers, it should permit exploration of multiple new avenues involving time domain experiments.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.