Evidence map›Paper›PMID 37384865›Full record

SynthesisJCO precision oncology2023

Prognostic Value of Neurotrophic Tyrosine Receptor Kinase Gene Fusions in Solid Tumors for Overall Survival: A Systematic Review and Meta-Analysis.

Ulrik Lassen, Carsten Bokemeyer, Jesus Garcia-Foncillas, Antoine Italiano, Gilles Vassal, Noman Paracha, Marisca Marian, Yuxian Chen, Louise Linsell, Keith Abrams

Erratum issuedOpen access · hybridAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in JCO precision oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Future oncology (London, England) · 2025
    Pooled it
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Ulrik LassenRigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-3865-4574
Carsten BokemeyerUniversity Medical Centre Hamburg Eppendorf, Hamburg, Germany.ORCID 0000-0001-6071-7810
Jesus Garcia-FoncillasDepartment of Oncology, University Cancer Institute, University Hospital Fundacion Jimenez Diaz, Autonomous University, Madrid, Spain.ORCID 0000-0002-7591-8006
Antoine ItalianoInstitut Bergonié, Bordeaux, France.ORCID 0000-0002-8540-5351
Gilles VassalGustave Roussy Comprehensive Cancer Center, Villejuif, France.ORCID 0000-0003-1780-8869
Noman ParachaBayer Pharmaceuticals, Basel, Switzerland.ORCID 0000-0002-3438-4853
Marisca MarianBayer Pharmaceuticals, Basel, Switzerland.
Yuxian ChenVisible Analytics, Oxford, United Kingdom.ORCID 0009-0007-5641-4017
Louise LinsellVisible Analytics, Oxford, United Kingdom.ORCID 0000-0003-3205-6511
Keith AbramsVisible Analytics, Oxford, United Kingdom.ORCID 0000-0002-7557-1567
Bayer (Switzerland) · CHHospital Universitario Fundación Jiménez Díaz · ESInstitut Gustave Roussy · FRInstitut Pprime · FRUniversität Hamburg · DEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEvidence suggests that neurotrophic tyrosine receptor kinase (

methodsA systematic literature review was conducted in Medline, Embase, Cochrane, and PubMed to identify studies comparing the overall survival (OS) of patients with

resultsIn the meta-analysis, the median follow-up ranged from 2 to 14 years and the median OS was between 10.1 and 12.7 months (where reported). Comparing patients with tumors

conclusionIn patients not treated with TRK inhibitor therapies, those with

Indexed as

NeoplasmsAdultBayes TheoremChildGene FusionHumansPrognosisReceptors, Amino AcidRetrospective StudiesReceptors, Amino Acidtyrosine receptor

Identifiers

PMID37384865
PMCPMC10581655
OpenAlexW4382517904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.