Evidence map›Paper›PMID 37384861›Full record

ArticleJCO global oncology2023

Childhood and Adolescent Cancer Care at a Tertiary Hospital in Northern Tanzania: A Retrospective Study.

Esther Majaliwa, Emily R Smith, Cesia Cotache-Condor, Hannah Rice, Yotham Gwanika, Julia Canick, Nelson Chao, Kristin Schroeder, Henry E Rice, Catherine Staton and 1 more

Abstract read
In one paragraph

Article in JCO global oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Esther MajaliwaPediatric Hematology and Oncology Services, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Emily R SmithDepartment of Emergency Medicine, Duke University Medical Center, Durham, NC.ORCID 0000-0002-1745-5728
Cesia Cotache-CondorDuke Global Health Institute, Duke University, Durham, NC.ORCID 0000-0002-3401-9565
Hannah RiceUniversity of North Carolina at Chapel Hill, Chapel Hill, NC.
Yotham GwanikaKilimanjaro Cancer Registry, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Julia CanickDuke Global Health Institute, Duke University, Durham, NC.ORCID 0000-0002-8353-4838
Nelson ChaoDepartment of Medicine, Duke University Medical Center, Durham, NC.
Kristin SchroederDepartment of Oncology, Bugando Medical Centre, Mwanza, Tanzania.ORCID 0000-0002-6433-6174
Henry E RiceDuke Global Health Institute, Duke University, Durham, NC.
Catherine StatonDepartment of Emergency Medicine, Duke University Medical Center, Durham, NC.ORCID 0000-0002-6468-2894
Blandina T MmbagaKilimanjaro Christian Medical University College, Moshi, Tanzania.

Funding

Improving access to cancer care for children in Tanzania: Designing a health-systems interventionK01TW012181 · FIC · DUKE UNIVERSITY · PI Emily Smith · 2022 to 2026
$816k
FIC NIH HHS K01 TW012181
6 · The paper itself

Abstract

purposeOver 400,000 children are diagnosed with cancer around the world each year, with over 80% of these children residing in low- and middle-income countries. This study aims to summarize the epidemiology and care patterns of newly diagnosed childhood cancer patients in Northern Tanzania.

methodsData from all children and adolescents (age 0-19 years) with newly diagnosed cancers were collected from the Kilimanjaro Cancer Registry located at the Kilimanjaro Christian Medical Centre. Descriptive and inferential analyses were used to compare the demographic and clinical characteristics of the participants over time, stage, and status at last contact. Statistical significance was set at

resultsA total of 417 patients were diagnosed with cancer between 2016 and 2021. There was an increase in the rate of patients with newly diagnosed pediatric cancer each year, particularly among children under age 5 years and 10 years. Leukemias and lymphomas were the leading diagnoses and accounted for 183 (43.8%) of all patients. Over 75% of patients were diagnosed at stage III or above. From a subset analysis of patients with available staging data (n = 101), chemotherapy was the most common treatment (87.1%), compared with radiotherapy and surgery.

conclusionThere is a significant burden of children with cancer in Tanzania. Our study fills crucial gaps in the literature related to the large burden of disease and survival for children with cancer in the Kilimanjaro region. Furthermore, our results can be used to understand the regional needs and guide research and strategic interventions to improve childhood cancer survival in Northern Tanzania.

Indexed as

NeoplasmsRadiation OncologyAdolescentAdultChildChild, PreschoolHumansInfantInfant, NewbornRetrospective StudiesTanzaniaTertiary Care CentersYoung Adult

Identifiers

PMID37384861
PMCPMC10497254

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.