ArticlePloS one2023
Incidence and treatment trends of infectious spondylodiscitis in South Korea: A nationwide population-based study.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 21 citations in OpenAlex.
- Global Priorities and Knowledge Gaps in Spinal Trauma, Infection, and Osteoporotic Fractures: Insights From the AO Spine Knowledge Forum Trauma & Infection Needs Assessment Survey.Global spine journal · 2026Article
- Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- An Atypical Presentation of Spondylodiscitis Following a Fall in an Elderly Patient: A Diagnostic Challenge.Cureus · 2026Article
- Infectious Spondylodiscitis of Bacterial Causes in Adults: Epidemiology, Pathophysiology, Diagnostic and Treatment Challenges.Microorganisms · 2026Review
- MRI spondylodiscitis severity index: A novel scoring system based on contrast-enhanced MRI of the spine for predicting the clinical course and severity of pyogenic spondylodiscitis.Skeletal radiology · 2026Article
- Concomitant osteoporotic vertebral compression fracture and infectious spondylitis in a patient with herpes zoster: A case report.Medicine · 2026Article
- Infectious Spondylitis Caused by Staphylococcus lugdunensis Following an L-PEN Procedure: A Case Report.Cureus · 2026Article
- Clinical features of Q fever vertebral osteomyelitis: case reports and literature review.Frontiers in medicine · 2026Article
- Clinical characteristics, microbiological landscape, and severity-stratified management of pyogenic spondylitis: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2026Observational
- Evaluation of the efficacy and safety of unilateral biportal endoscopic technique for the treatment of infectious spondylitis.American journal of translational research · 2026Article
- Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2025Article
- Infectious spondylodiscitis: Epidemiology, diagnosis, microbiological findings, clinical features and outcomes in a 14-year retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Risk Factor Analysis of Simple Drainage Followed by Instrumented Fusion in Patients with Pyogenic Spinal Infection.Journal of Korean Neurosurgical Society · 2025Article
- Article
- Sagittal Parameters and Clinical Outcomes in Cervical Spondylitis: The Cohort Analysis.Diseases (Basel, Switzerland) · 2025Article
- Etiological Insights and the Role of Individual Factors in Infectious Spondylodiscitis.Infectious disease reports · 2025Article
- Hematologic Inflammation Indices for Differentiating between Brucella, Pyogenic, and Tuberculous Spondylodiscitis.Biomedicines · 2024Article
- Minimally Invasive versus Traditional Surgery: Efficacy of PELD and PLIF in Treating Pyogenic Spondylodiscitis.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Epidemiology and management of infectious spondylitis in Korea: a narrative review.Ewha medical journal · 2024Review
- Imaging of Spondylodiscitis: A Comprehensive Updated Review-Multimodality Imaging Findings, Differential Diagnosis, and Specific Microorganisms Detection.Microorganisms · 2024Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of infectious spondylodiscitis (IS) has increased in recent years due to an increase in the numbers of older patients with chronic diseases, as well as patients with immunocompromise, steroid use, drug abuse, invasive spinal procedures, and spinal surgeries. However, research focusing on IS in the general population is lacking. This study investigated the incidence and treatment trends of IS in South Korea using data obtained from the Health Insurance Review and Assessment Service. A total of 169,244 patients (mean age: 58.0 years) diagnosed from 2010 to 2019 were included in the study. A total of 10,991 cases were reported in 2010 and 18,533 cases in 2019. Hence, there was a 1.5-fold increase in incidence rate per 100,000 people from 22.90 in 2010 to 35.79 in 2019 (P < 0.05). The incidence rate of pyogenic spondylodiscitis per 100,000 people increased from 15.35 in 2010 to 33.75 in 2019, and that of tuberculous spondylodiscitis decreased from 7.55 in 2010 to 2.04 in 2019 (P < 0.05, respectively). Elderly individuals ≥ 60 years of age accounted for 47.6% (80,578 patients) of all cases of IS. The proportion of patients who received conservative treatment increased from 82.4% in 2010 to 85.8% in 2019, while that of patients receiving surgical treatment decreased from 17.6% to 14.2% (P < 0.05, respectively). Among surgical treatments, the proportions of corpectomy and anterior fusion declined, while proportion of incision and drainage increased (P < 0.05, respectively). The total healthcare costs increased 2.9-fold from $29,821,391.65 in 2010 to $86,815,775.81 in 2019 with a significant increase in the ratio to gross domestic product. Hence, this population-based cohort study demonstrated that the incidence rate of IS has increased in South Korea. The conservative treatment has increased, while the surgical treatment has decreased. The socioeconomic burden of IS has increased rapidly.
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