Evidence map›Paper›PMID 37384372›Full record

ArticleJournal of medical Internet research2023

Evaluating the Supporting Evidence of Medical Cannabis Claims Made on Clinic Websites: Cross-Sectional Study.

Braden O'Neill, Jacob Ferguson, Lauren Dalueg, Abban Yusuf, Abirami Kirubarajan, Taryn Lloyd, Eisi Mollanji, Navindra Persaud

Open access · goldAbstract read
In one paragraph

Article in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Braden O'NeillDepartment of Family and Community Medicine, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.ORCID 0000-0003-2164-8263
Jacob FergusonTemerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-4512-4280
Lauren DaluegUniversity College Dublin, Dublin, Ireland.ORCID 0009-0004-6646-2010
Abban YusufMAP Centre for Urban Health Solutions, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.ORCID 0000-0001-6189-6857
Abirami KirubarajanDepartment of Obstetrics and Gynaecology, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.ORCID 0000-0001-9807-5024
Taryn LloydDepartment of Emergency Medicine, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.ORCID 0000-0001-5858-4465
Eisi MollanjiFaculty of Medicine, University of Ottawa, Ottawa, ON, Canada.ORCID 0000-0002-9159-5729
Navindra PersaudDepartment of Family and Community Medicine, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.ORCID 0000-0003-3327-5580
St. Michael's Hospital · CAMcMaster University · CAUniversity College Dublin · IEUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince the legalization of medical cannabis in Canada in 2013, prescription of cannabis for medical purposes has become commonplace and a multibillion dollar industry has formed. Much of the media coverage surrounding medical cannabis has been positive in nature, leading to Canadians potentially underestimating the adverse effects of medical cannabis use. In recent years, there has been a large increase in clinic websites advertising the use of medical cannabis for health indications. However, little is known about the quality of the evidence used by these clinic websites to describe the effectiveness of cannabis used for medical purposes.

objectiveWe aimed to identify the indications for medical cannabis reported by cannabis clinics in Ontario, Canada, and the evidence these clinics cited to support cannabis prescription.

methodsWe conducted a cross-sectional web search to identify all cannabis clinic websites within Ontario, Canada, that had physician involvement and identified their primary purpose as cannabis prescription. Two reviewers independently searched these websites to identify all medical indications for which cannabis was promoted and reviewed and critically appraised all studies cited using the Oxford Centre for Evidence-Based Medicine Levels of Evidence rubric.

resultsA total of 29 clinics were identified, promoting cannabis for 20 different medical indications including migraines, insomnia, and fibromyalgia. There were 235 unique studies cited on these websites to support the effectiveness of cannabis for these indications. A high proportion (36/235, 15.3%) of the studies were identified to be at the lowest level of evidence (level 5). Only 4 clinic websites included any mention of harms associated with cannabis.

conclusionsCannabis clinic websites generally promote cannabis use as medically effective but cite low-quality evidence to support these claims and rarely discuss harms. The recommendation of cannabis as a general therapeutic for many indications unsupported by high-quality evidence is potentially misleading for medical practitioners and patients. This disparity should be carefully evaluated in context of the specific medical indication and an individualized patient risk assessment. Our work illustrates the need to increase the quality of research performed on the medical effects of cannabis.

Indexed as

CannabisMedical MarijuanaAdvertisingCross-Sectional StudiesHumansOntarioMedical Marijuanaadverse effectscannabisconsumer health informationevidence-based medicine

Identifiers

PMID37384372
PMCPMC10365571
OpenAlexW4382502305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.